Plexin-C1 Antibodies

AND PLXNC1 ELISA kits, Plexin-C1 Proteins

Many biological assays use antibodies to detect Plexin-C1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plexin-C1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plexin-C1 antibodies...

We validate the specificity of these antibodies to Plexin-C1 by testing them on tissues known to express PLXNC1 positively and negatively. Browse below to find the PLXNC1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLXNC1 Infographic by Boster Bio

All PLXNC1 Products

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Specificity

Applications

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Anti-CD232 PLXNC1 Antibody

7 Q&As

Western Blot analysis of 3T3 cells using CD232 Polyclonal Antibody

Western Blot analysis of 3T3 cells using CD232 Polyclonal Antibody diluted at 1:1000

Human, Mouse, Rat

ELISA, WB

$399
Cat # A10941
100μl

Mouse Plexin C1/PLXNC1 ELISA Kit PicoKine®

6 Q&As

Mouse

ELISA

$750
Cat # EK1829
96 wells/kit, with removable strips.

PLXNC1 (NM_005761) Human Recombinant Protein

Coomassie blue staining of purified PLXNC1 protein

$1249
Cat # PROTO60486
20 µg

PLXNC1 (NM_005761) Human Over-expression Lysate

Human

$960
Cat # LS010154
20 µg, 100 µg

Anti-PLXNC1 Antibody Picoband®

Western blot analysis of PLXNC1 using anti-PLXNC1 antibody (A10941-1)

Flow Cytometry analysis of HepG2 cells using anti-PLXNC1 antibody (A10941-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A10941-1
100 µg/vial

PLXNC1 Overview

Facts about Plexin-C1.

PLXNC1 3D structure. Source: alphafold

Plexin-C1 (PLXNC1)

Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses resulting in the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).

Gene Information

Human
Gene Name:	PLXNC1
Uniprot:	O60486
Entrez:	10154

Family

Belongs to:

plexin family

Alternative Names

CD232 antigen; CD232; plexin (semaphorin receptor); Plexin C1; PLXNC1; PLXN-C1; receptor for viral semaphorin protein; receptor for virally-encoded semaphorin; VESPR; VESPRplexin-C1; Virus-encoded semaphorin protein receptor

Molecular Weight

Mass (kDA):
175.742 kDA

Genomic Context


Human

Location:	12q22
Sequence:	12; NC_000012.12 (94148577..94307675)

Tissue Specificity

Detected in heart, brain, lung, spleen and placenta.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Cell Invasion
Adenocarcinoma
Neoplasm Metastasis
Leukemogenesis
Childhood Acute Myeloid Leukemia
Exophthalmos
Melanoma
Strabismus
Esotropia
Hematopoietic Neoplasms
Leukemia, Myelocytic, Acute

Neoplasms
Obesity
Myeloid Leukemia
Nervousness
Pancreatic Neoplasm
Leukemia
Malignant Neoplasm Of Pancreas

Interacting Proteins

SEMA7A

Pathways

Cell Migration
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLXNC1

References

PMID: 9586637 by Comeau M.R., et al. A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR.

PMID: 20727575 by Liu H., et al. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1.