PMAIP1 Antibodies

AND PMAIP1 ELISA kits, PMAIP1 Proteins

Many biological assays use antibodies to detect PMAIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PMAIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PMAIP1 antibodies...

We validate the specificity of these antibodies to PMAIP1 by testing them on tissues known to express PMAIP1 positively and negatively. Browse below to find the PMAIP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PMAIP1 Infographic by Boster Bio

All PMAIP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Noxa Rabbit Monoclonal Antibody

3 Citations 1 Q&As

Western blot analysis of PMAIP1 using anti-PMAIP1 antibody (M02287)

Human, Mouse, Rat

$370
Cat # M02287
100 μl

Anti-Noxa Pmaip1 Antibody

Western blot analysis of Noxa in human stomach tissue lysate with Noxa antibody at (A) 0

Immunohistochemistry of NOXA in human stomach tissue with NOXA antibody at 2

Immunofluorescence of Noxa in Human Stomach cells with Noxa antibody at 10 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A02287
0.1 mg

Anti-Noxa PMAIP1 Antibody

Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Noxa antibody

Human

Flow Cytometry, IHC, WB

$405
Cat # A02287-1
100ul

Noxa (PMAIP1) (NM_021127) Human Over-expression Lysate

Human

$628
Cat # LS005366
20 µg, 100 µg

PMAIP1 Overview

Facts about Phorbol-12-myristate-13-acetate-induced protein 1.

PMAIP1 3D structure. Source: alphafold

Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)

Promotes activation of caspases and apoptosis. Promotes adrenal gland changes and efflux of apoptogenic proteins from the mitochondria.

Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Gene Information

Human
Gene Name:	PMAIP1
Uniprot:	Q13794
Entrez:	5366

Family

Belongs to:

PMAIP1 family

Alternative Names

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; NOXAPMA-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; Protein Noxa

Molecular Weight

Mass (kDA):
6.03 kDA

Genomic Context


Human

Location:	18q21.32
Sequence:	18; NC_000018.10 (59899996..59904305)

Tissue Specificity

Highly expressed in adult T-cell leukemia cell line.

Subcellular Localizations

Mitochondrion.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Lymphoma
Melanoma
Carcinoma
Malignant Paraganglionic Neoplasm
Multiple Myeloma
Lymphoid Leukemia
Chronic Lymphocytic Leukemia
B-cell Lymphomas
Cell Transformation, Neoplastic

Malignant Neoplasm Of Breast
Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse
Mammary Neoplasms
Malignant Neoplasm Of Lung
Endoplasmic Reticulum Stress
Genotoxic Stress
Lung Neoplasms

Interacting Proteins

BCL2
MCL1

Pathways

Cell Death
Induction Of Apoptosis
Cell Cycle
Cell Cycle Arrest
Rna Interference
Cell Growth
Autophagy
Cell Proliferation
Cell Differentiation
Sensitization
Drug Resistance
Pathogenesis

Cell Killing
Mitochondrial Depolarization
Localization
Release Of Cytochrome C From Mitochondria
Glycolysis
Programmed Cell Death
Immune Response

PTMs

Cleavage
Phosphorylation
Ubiquitination
Acetylation
Methylation

Deacetylation
Dephosphorylation
Sumoylation
Demethylation
Reduction

Research Areas

Apoptosis
Cancer
Cellular Markers
Lipid and Metabolism
Membrane Trafficking and Chaperones

Mitochondrial-Mediated Pathway
Plasma Membrane Markers
Stem Cell Markers
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMAIP1

References

PMID: 2398525 by Hijikata M., et al. Molecular cloning and characterization of a cDNA for a novel phorbol- 12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line.

PMID: 10807576 by Oda E., et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.