PNPO Antibodies

AND PNPO ELISA kits, PNPO Proteins

Many biological assays use antibodies to detect PNPO, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PNPO in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PNPO antibodies...

We validate the specificity of these antibodies to PNPO by testing them on tissues known to express PNPO positively and negatively. Browse below to find the PNPO antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: SHQ1

PNPO Infographic by Boster Bio

All PNPO Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

PNPO (NM_018129) Human Recombinant Protein

Coomassie blue staining of purified PNPO protein

$1249
Cat # PROTQ9NVS9
20 µg

Anti-PNPO Mouse Monoclonal Antibody [Clone ID: OTI3B3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNPO (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PNPO monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Anti-PNPO mouse monoclonal antibody (M06357-1) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNPO

Dog, Human, Monkey, Mouse, Rat

IF, WB

$523
Cat # M06357-1
100 µl

Anti-PNPO Mouse Monoclonal Antibody [Clone ID: OTI1G9]

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PNPO mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PNPO mouse monoclonal antibody

+12

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M06357
100 µl

PNPO (NM_018129) Human Over-expression Lysate

Human

$628
Cat # LS055163
20 µg, 100 µg

Anti-PNPO Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, WB

$370
Cat # A06357-1
100 μl/vial

PNPO Overview

Facts about Pyridoxine-5'-phosphate oxidase.

PNPO 3D structure. Source: alphafold

Pyridoxine-5'-phosphate oxidase (PNPO)

Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) to pyridoxal 5'-phosphate (PLP). .

Gene Information

Human
Gene Name:	PNPO
Uniprot:	Q9NVS9
Entrez:	55163

Family

Belongs to:

pyridoxamine 5'-phosphate oxidase family

Alternative Names

EC 1.4.3.5; FLJ10535; PDXPO; pyridoxal 5'-phosphate synthase; pyridoxamine 5'-phosphate oxidase; Pyridoxamine-phosphate oxidase; pyridoxine 5'-phosphate oxidase; pyridoxine-5'-phosphate oxidase

Molecular Weight

Mass (kDA):
29.988 kDA

Genomic Context


Human

Location:	17q21.32
Sequence:	17; NC_000017.11 (47941524..47949308)

Diseases

Epilepsy
Encephalopathies
Epilepsy, Pyridoxine-dependent
Hypokinesia
Malignant Neoplasms
Vitamin B 6 Deficiency
Brain Diseases, Metabolic, Inborn
Epilepsies, Myoclonic
Hypophosphatasia
Inborn Errors Of Metabolism
Hypertensive Disease

Cholangiocarcinoma
Abnormal Behavior
Succinate-semialdehyde Dehydrogenase Deficiency
Essential Hypertension
Early Infantile Epileptic Encephalopathy With Burst-suppression
Malignant Neoplasm Of Breast

Pathways

Transport
Nucleosome Assembly
Aging
Pathogenesis

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PNPO

References

PMID: 12824491 by Musayev F.N., et al. Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase.

PMID: 15772097 by Mills P.B., et al. Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase.