PRODH Antibodies

AND PRODH ELISA kits, PRODH Proteins

Many biological assays use antibodies to detect PRODH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRODH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRODH antibodies...

We validate the specificity of these antibodies to PRODH by testing them on tissues known to express PRODH positively and negatively. Browse below to find the PRODH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PRODH? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PRODH IHC Guide

PRODH Infographic by Boster Bio

All PRODH Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PRODH Antibody Picoband®

Western blot analysis of PRODH using anti-PRODH antibody (A03231-3)

IHC analysis of PRODH using anti-PRODH antibody (A03231-3)

Flow Cytometry analysis of RT4 cells using anti-PRODH antibody (A03231-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A03231-3
100 µg/vial

PRODH (NM_016335) Human Over-expression Lysate

Human

$960
Cat # LS005625
20 µg, 100 µg

PRODH2 (NM_021232) Human Over-expression Lysate

Human

$960
Cat # LS058510
20 µg, 100 µg

PRODH Overview

Facts about Proline dehydrogenase 1, mitochondrial.

PRODH 3D structure. Source: alphafold

Proline dehydrogenase 1, mitochondrial (PRODH)

Converts proline to delta-1-pyrroline-5-carboxylate. .

Gene Information

Human
Gene Name:	PRODH
Uniprot:	O43272
Entrez:	5625

Family

Belongs to:

proline oxidase family

Alternative Names

EC 1.5.99.8; FLJ33744; HSPOX2; mitochondrial; p53-induced gene 6 protein; PIG6MGC148078; POX2; PRODH2MGC148079; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase ); Proline oxidase; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6

Molecular Weight

Mass (kDA):
68.002 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (18912781..18936553, complement)

Tissue Specificity

Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Schizophrenia
Digeorge Syndrome
Proline Dehydrogenase Deficiency
Psychotic Disorders
Malignant Neoplasms
Neoplasms
Mental Disorders
22q11 Deletion Syndrome
Bipolar Disorder
Schizoaffective Disorder
Haploinsufficiency
Physiological Stress

Hypoxia
Dehydration
Cell Transformation, Neoplastic
Dysequilibrium Syndrome
Autistic Disorder
Malnutrition
Epilepsy

Pathways

Cell Death
Transport
Prepulse Inhibition
Pathogenesis
Electron Transport
Hypersensitivity
Autophagy
Programmed Cell Death
Tricarboxylic Acid Cycle
Electron Transport Chain
Urea Cycle
Disease Resistance
Protein Palmitoylation

Cellular Homeostasis
Aging
Proteolysis
Neurogenesis
Nodulation
Fermentation
System Development

PTMs

Oxidation
Methylation

Reduction
Phosphorylation

Nitration

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRODH

References

PMID: 9385373 by Campbell H.D., et al. A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia.

PMID: 10192398 by Gogos J.A., et al. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice.