This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Peroxiredoxin-like 2A.
Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (By similarity). May influence bone resorption and help to maintain bone mass (By similarity).
| Mouse | |
|---|---|
| Gene Name: | Prxl2a |
| Uniprot: | Q9CYH2 |
| Entrez: | 70564 |

| Belongs to: |
|---|
| peroxiredoxin-like PRXL2 family |

C10orf58; Chromosome 10 Open Reading Frame 58; Family With Sequence Similarity 213, Member A; PAMM; Peroxiredoxin (PRX)-Like 2 Activated In M-CSF Stimulated Monocytes; Peroxiredoxin-Like 2 Activated In M-CSF Stimulated Monocytes; Protein PAMM; Redox-Regulatory Protein PAMM; UPF0765 Protein C10orf58
Mass (kDA):
24.395 kDA

| Mouse | |
|---|---|
| Location: | 14|14 B |
| Sequence: | 14; |
Expressed in kidney, liver, skin, and brain (PubMed:19951071). Widely expressed with highest levels detected in adipose tissue (PubMed:26438880).

PMID: 19951071 by Xu Y., et al. PAMM: a redox regulatory protein that modulates osteoclast differentiation.
PMID: 26438880 by Guo F., et al. Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling.