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- Table of Contents
Prosaposin Antibodies
AND PSAP ELISA kits, Prosaposin Proteins
Many biological assays use antibodies to detect Prosaposin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prosaposin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prosaposin antibodies...
Designing a Western blot for Prosaposin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PSAP Western Blot GuideDesigning an IHC experiment for Prosaposin? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PSAP IHC GuidePSAP Infographic by Boster Bio
All PSAP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, IHC-F, WB
$370
Cat # PB9390
100 μg/vial
Cat # PB9390
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00937-1
100 µg/vial
Cat # A00937-1
100 µg/vial
PSAP Overview
Facts about Prosaposin.
Prosaposin (PSAP)
Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.
1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.
Gene Information
| Human | |
|---|---|
| Gene Name: | PSAP |
| Uniprot: | P07602 |
| Entrez: | 5660 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ00245; GLBA; proactivator polypeptide; prosaposin; PSAP; SAP1; SAP1MGC110993; sphingolipid activator protein-1
Molecular Weight
Mass (kDA):
58.113 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q22.1 |
| Sequence: | 10; NC_000010.11 (71816298..71851251, complement) |
Subcellular Localizations
Lysosome.; [Prosaposin]: Secreted. Secreted as a fully glycosylated 70 kDa protein composed of complex glycans.
Diseases
- Neoplasms
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Malignant Neoplasms
- Carcinoma
- Gaucher Disease
- Adenocarcinoma
- Leukodystrophy, Metachromatic
- Leukodystrophy
- Nervousness
- Lysosomal Storage Diseases
- Neoplasm Metastasis
Interacting Proteins
- CASP14
- VCP
- ZBED1
Pathways
- Localization
- Transport
- Secretion
- Cell Death
- Glycosylation
- Endocytosis
- Translation
- Pathogenesis
- Cell Proliferation
- Regeneration
- Proteolysis
- Lipid Storage
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Biotinylation
- Methylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSAP
bosterbio.com/bosterbio-gene-info-cards/PSAP
References
PMID: 2515150 by Rorman E.G., et al. Molecular cloning of a human co-beta-glucosidase cDNA: evidence that four sphingolipid hydrolase activator proteins are encoded by single genes in humans and rats.
PMID: 2498298 by Nakano T., et al. Structure of full-length cDNA coding for sulfatide activator, a Co- beta-glucosidase and two other homologous proteins: two alternate forms of the sulfatide activator.
5 Publications of Boster Prosaposin Antibodies & ELISA Kits
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2009.17.010, Effect of epidermal growth factor and dexamethasone on fetal rat lung developmen...
- PubMed ID: 10.1007/s10571-016-0423-7, Expression of SHANK3 in the Temporal Neocortex of Patients with Intractable Temp...
- PubMed ID: 26640562, Effects of bone marrow-derived mesenchymal stem cells transfected with survivin ...
- PubMed ID: 24596465, Alterations in the endometrium of rats, rabbits, and?Macaca mulatta?that receive...
- PubMed ID: 23671638, Wu Y, You H, Ma P, Li L, Yuan Y, Li J, Ye X, Liu X, Yao H, Chen R, Lai K, Yang X...
*More publications can be found for each product on its corresponding product page