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- Table of Contents
PTPRA Antibodies
AND PTPRA ELISA kits, PTPRA Proteins
Many biological assays use antibodies to detect PTPRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRA antibodies...
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PTPRA Infographic by Boster Bio
All PTPRA Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A03280Y798
100ul
Cat # A03280Y798
100ul
PTPRA Overview
Facts about Receptor-type tyrosine-protein phosphatase alpha.
Receptor-type tyrosine-protein phosphatase alpha (PTPRA)
Gene Information
| Human | |
|---|---|
| Gene Name: | PTPRA |
| Uniprot: | P18433 |
| Entrez: | 5786 |
Family
| Belongs to: |
|---|
| protein-tyrosine phosphatase family |
Alternative Names
EC 3.1.3.48; HEPTP; HLPR; LRP; LRPHPTPalpha; protein tyrosine phosphatase, receptor type, A; Protein-tyrosine phosphatase alpha; PTP alpha; PTPAreceptor type, alpha polypeptide; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; receptor-type tyrosine-protein phosphatase alpha; RPTPA; R-PTP-alpha; tyrosine phosphatase alpha
Molecular Weight
Mass (kDA):
90.719 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p13 |
| Sequence: | 20; NC_000020.11 (2864195..3038669) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Localizes to focal adhesion sites following integrin engagement.
Diseases
- Posttransfusion Purpura
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasms
- Insulin Resistance
- Carcinoma
- Diabetes Mellitus
- Nervousness
- Mammary Neoplasms
- Liver Carcinoma
- Malignant Neoplasm Of Breast
- Diabetes Mellitus, Non-insulin-dependent
- Cell Transformation, Neoplastic
Interacting Proteins
- EGFR
- Fyn
- GRB2
- SRC
Pathways
- Cell Adhesion
- Cell Growth
- Localization
- Cell Migration
- Secretion
- Cell Activation
- Cell Motility
- Cell Differentiation
- Pathogenesis
- Innervation
- Mammary Gland Development
- Axon Guidance
- Cell Proliferation
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Oxidation
- Acetylation
Research Areas
- GPCR
- Protein Phosphatase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRA
bosterbio.com/bosterbio-gene-info-cards/PTPRA
References
PMID: 2169617 by Kaplan R., et al. Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.
PMID: 2170109 by Krueger N.X., et al. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.