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- Table of Contents
Facts about UL16-binding protein 6.
| Human | |
|---|---|
| Gene Name: | RAET1L |
| Uniprot: | Q5VY80 |
| Entrez: | 154064 |

| Belongs to: |
|---|
| MHC class I family |

UL16-binding protein 6
Mass (kDA):
27.509 kDA

| Human | |
|---|---|
| Location: | 6q25.1 |
| Sequence: | 6; NC_000006.12 (150018334..150025532, complement) |
Widely expressed (PubMed:11827464). Expressed in trachea (PubMed:19658097). Constitutively expressed in peripheral blood mononuclear cells, including B-cells and natural killer cells, as well as CD4+ and CD8+ T-cells and monocytes. Tends to be up-regulated in various lymphoid malignancies, including chronic lymphocytic leukemia (PubMed:28559451).
Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. In CMV-infected fibroblasts, detected intracellularly.



PMID: 11827464 by Radosavljevic M., et al. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.
PMID: 19658097 by Eagle R.A., et al. ULBP6/RAET1L is an additional human NKG2D ligand.