RALGPS1 Antibodies

AND RALGPS1 ELISA kits, RALGPS1 Proteins

Many biological assays use antibodies to detect RALGPS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RALGPS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RALGPS1 antibodies...

We validate the specificity of these antibodies to RALGPS1 by testing them on tissues known to express RALGPS1 positively and negatively. Browse below to find the RALGPS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RALGPS1 Infographic by Boster Bio

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RALGPS1 (NM_001190729) Human Over-expression Lysate

RALGPS1 Human Over-expression Lysates NM_001190728

Human

$628
Cat # LS009649
20 µg, 100 µg

RALGPS1 Overview

Facts about Ras-specific guanine nucleotide-releasing factor RalGPS1.

RALGPS1 3D structure. Source: alphafold

Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1)

Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity).

Guanine nucleotide exchange factor for. .

Gene Information

Human
Gene Name:	RALGPS1
Uniprot:	Q5JS13
Entrez:	9649

Family

Belongs to:

No superfamily

Alternative Names

KIAA0351RalGEF 2; Ral GEF with PH domain and SH3 binding motif 1; Ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor 2; Ral guanine nucleotide exchange factor RalGPS1A; RalA exchange factor RalGPS1; RALGEF2RALGPS1A; ras-specific guanine nucleotide-releasing factor RalGPS1

Molecular Weight

Mass (kDA):
62.133 kDA

Genomic Context


Human

Location:	9q33.3
Sequence:	9; NC_000009.12 (126914774..127223166)

Tissue Specificity

Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus.

Subcellular Localizations

Cytoplasm. Cell membrane. Associates with membranes through the PH domain.

Diseases

Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Leukemia
Proteinuria Of Undiagnosed Cause
Philadelphia Chromosome
Prader-willi Syndrome
Acute Lymphocytic Leukemia

Pathways

Methylation
Glomerular Filtration

PTMs

Methylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RALGPS1

References

PMID: 10747847 by Rebhun J.F., et al. Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral.

PMID: 10889189 by de Bruyn K.M., et al. RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral.