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- Table of Contents
Facts about Receptor activity-modifying protein 3.
Acts as a receptor for adrenomedullin (AM) together with CALCRL. .
Human | |
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Gene Name: | RAMP3 |
Uniprot: | O60896 |
Entrez: | 10268 |
Belongs to: |
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RAMP family |
calcitonin receptor-like receptor activity modifying protein 3; Calcitonin-receptor-like receptor activity-modifying protein 3; CRLR activity-modifying protein 3; RAMP3; receptor (calcitonin) activity modifying protein 3; receptor (G protein-coupled) activity modifying protein 3; receptor activity modifying protein 3; receptor activity-modifying protein 3; receptor-activity-modifying protein 3
Mass (kDA):
16.518 kDA
Human | |
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Location: | 7p13 |
Sequence: | 7; NC_000007.14 (45157778..45184250) |
Strongly expressed in lung, breast, immune system and fetal tissues.
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Moves from intracellular puncta to the plasma membrane in a RAMP3-dependent manner.
PMID: 9620797 by McLatchie L.M., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.
PMID: 23674134 by Lenhart P.M., et al. G-protein-coupled receptor 30 interacts with receptor activity- modifying protein 3 and confers sex-dependent cardioprotection.