RASA1 Antibodies

AND RASA1 ELISA kits, RASA1 Proteins

Many biological assays use antibodies to detect RASA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RASA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RASA1 antibodies...

We validate the specificity of these antibodies to RASA1 by testing them on tissues known to express RASA1 positively and negatively. Browse below to find the RASA1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for RASA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the RASA1 Western Blot Guide

RASA1 Infographic by Boster Bio

All RASA1 Products

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Applications

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Anti-RASA1 Antibody Picoband®

1 Citations

Western blot analysis of RASA1 using anti-RASA1 antibody (PB9796)

IF analysis of RASA1 using anti-RASA1 antibody (PB9796)

Flow Cytometry analysis of U87 cells using anti-RASA1 antibody (PB9796)

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # PB9796
100 μg/vial

Anti-RASA1 Rabbit Monoclonal Antibody

Western blot analysis of RASA1 expression in Rat brain cell lysate

Human, Rat

IHC, WB

$370
Cat # M01929-1
100 μl/vial

RASA1 (NM_002890) Human Over-expression Lysate

Human

$628
Cat # LS005921
20 µg, 100 µg

RASA1 Overview

Facts about Ras GTPase-activating protein 1.

RASA1 3D structure. Source: alphafold

Ras GTPase-activating protein 1 (RASA1)

Inhibitory regulator of This Ras-cyclic AMP pathway.
Stimulates the GTPase of ordinary but not oncogenic Ras p21; this stimulation might be further increased in the presence of NCK1.

Gene Information

Human
Gene Name:	RASA1
Uniprot:	P20936
Entrez:	5921

Family

Belongs to:

No superfamily

Alternative Names

CM-AVM; PKWS; RASA1; RasGAP; Ras-GAP

Molecular Weight

Mass (kDA):
116.403 kDA

Genomic Context


Human

Location:	5q14.3
Sequence:	5; NC_000005.10 (87267845..87391926)

Tissue Specificity

In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level).

Subcellular Localizations

Cytoplasm.

Diseases

Arteriovenous Malformation
Vascular Anomaly
Malignant Neoplasms
Neoplasms
Sturge-weber Syndrome
Klippel-trenaunay-weber Syndrome
Capillary Malformation (disorder)
Congenital Vascular Anomaly
Hypertrophy
Pathologic Fistula
Port-wine Stain
Skin Neoplasms

Hereditary Hemorrhagic Telangiectasia
Hemangioma
Arteriovenous Fistula
Tumor Angiogenesis
Pathologic Neovascularization
Strawberry Nevus Of Skin
Tissue Adhesions

Interacting Proteins

ABI1
AR
CAPNS1
CAV1
DLC1

EGFR
ERBB2
ERBB3
FLT3
GAB1

KIT
MET
NCK1
PDGFRB

Pathways

Pathogenesis
Cell Proliferation
Vasculogenesis
Angiogenesis
Cell Motility
Rna Interference
Germinal Center Formation
Cell Development
Dna Repair
Virulence
Localization
Cytokinesis
Reverse Transcription

Dna Amplification
Translation
Cell Cycle
Cell Differentiation
Cell Growth
Wound Healing
Regulation Of Cell Growth

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RASA1

References

PMID: 3201259 by Trahey M., et al. Molecular cloning of two types of GAP complementary DNA from human placenta.

PMID: 8360177 by Zhang Y., et al. Purification, characterization, and cellular localization of the 100- kDa human placental GTPase-activating protein.