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- Table of Contents
1 Citations 1 Q&As
Facts about Ras GTPase-activating protein 1.
Inhibitory regulator of This Ras-cyclic AMP pathway.
Stimulates the GTPase of ordinary but not oncogenic Ras p21; this stimulation might be further increased in the presence of NCK1..
| Human | |
|---|---|
| Gene Name: | RASA1 |
| Uniprot: | P20936 |
| Entrez: | 5921 |

| Belongs to: |
|---|
| No superfamily |

CM-AVM; PKWS; RASA1; RasGAP; Ras-GAP
Mass (kDA):
116.403 kDA

| Human | |
|---|---|
| Location: | 5q14.3 |
| Sequence: | 5; NC_000005.10 (87267845..87391926) |
In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level).
Cytoplasm.





PMID: 3201259 by Trahey M., et al. Molecular cloning of two types of GAP complementary DNA from human placenta.
PMID: 8360177 by Zhang Y., et al. Purification, characterization, and cellular localization of the 100- kDa human placental GTPase-activating protein.