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- Table of Contents
Designing an IHC experiment for RASAL3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RASAL3 IHC GuideFacts about RAS protein activator like-3.
Functions as a Ras GTPase-activating protein.
Plays an essential role in the growth and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down-stream ERK signaling pathway..
| Human | |
|---|---|
| Gene Name: | RASAL3 |
| Uniprot: | Q86YV0 |
| Entrez: | 64926 |

| Belongs to: |
|---|
| No superfamily |

RAS Protein Activator Like 3; RAS Protein Activator Like-3
Mass (kDA):
111.898 kDA

| Human | |
|---|---|
| Location: | 19p13.12 |
| Sequence: | 19; NC_000019.10 (15451624..15464571, complement) |
Predominantly expressed in cells of hematopoietic lineages.
Cytoplasm. Cytoplasm, cell cortex.


PMID: 25652366 by Saito S., et al. RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells.