RASGEF1A Antibodies

AND RASGEF1A ELISA kits, RASGEF1A Proteins

Many biological assays use antibodies to detect RASGEF1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RASGEF1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RASGEF1A antibodies...

We validate the specificity of these antibodies to RASGEF1A by testing them on tissues known to express RASGEF1A positively and negatively. Browse below to find the RASGEF1A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RASGEF1A Infographic by Boster Bio

All RASGEF1A Products

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Product

Figures

Specificity

Applications

Price

Anti-RGF1A RASGEF1A Antibody

Human

ELISA, WB

$380
Cat # A14628
100ul

RASGEF1A (NM_145313) Human Over-expression Lysate

Human

$628
Cat # LS221002
20 µg, 100 µg

RASGEF1A Overview

Facts about Ras-GEF domain-containing family member 1A.

RASGEF1A 3D structure. Source: alphafold

Ras-GEF domain-containing family member 1A (RASGEF1A)

Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.

Gene Information

Human
Gene Name:	RASGEF1A
Uniprot:	Q8N9B8
Entrez:	221002

Family

Belongs to:

No superfamily

Alternative Names

CG4853 gene product; CG4853; FLJ37817; RasGEF domain family, member 1A; ras-GEF domain-containing family member 1A

Molecular Weight

Mass (kDA):
54.556 kDA

Genomic Context


Human

Location:	10q11.21
Sequence:	10; NC_000010.11 (43194533..43267065, complement)

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Cholangiocarcinoma
Embryonal Carcinoma
Bile Duct Neoplasms
Teratoma
Seminoma
Malignant Neoplasm Of Lung
Carcinoma
Hirschsprung Disease
Solid Tumor

Testicular Neoplasms
Lung Neoplasms
Non-small Cell Lung Carcinoma
Intrahepatic Cholangiocarcinoma
Allelic Imbalance
Testicular Embryonal Carcinoma
Yolk Sac Tumor

Pathways

Cell Adhesion
Regulation Of Cell Adhesion
Pathogenesis

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RASGEF1A

References

PMID: 17121879 by Ura K., et al. Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.

PMID: 19645719 by Yaman E., et al. RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2- specific nucleotide exchange.