RBL1 Antibodies

AND RBL1 ELISA kits, RBL1 Proteins

Many biological assays use antibodies to detect RBL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RBL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RBL1 antibodies...

We validate the specificity of these antibodies to RBL1 by testing them on tissues known to express RBL1 positively and negatively. Browse below to find the RBL1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RBL1 Infographic by Boster Bio

All RBL1 Products

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Anti-p107/RBL1 Antibody Picoband®

4 Q&As

Anti-p107 antibody, PA1894, Western blottingLane 1: 239T Cell LysateLane 2: JURKAT Cell Lysate

Anti-p107 antibody, PA1894, IHC(P)IHC(P): Human Intestinal Cancer Tissue

Anti-p107 antibody, PA1894, IHC(P)IHC(P): Rat Intestine Tissue

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1894
100 μg/vial

Anti-Phospho-p107 (T369) RBL1 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A03008T369
100ul

Anti-p107 (RBL1) Mouse Monoclonal Antibody [Clone ID: OTI4E1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RBL1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 293T cell line by using anti-RBL1 monoclonal antibody (1:500)

Human, Mouse, Rat

$523
Cat # M03008
100 µl

p107 (RBL1) (NM_183404) Human Over-expression Lysate

Human

$628
Cat # LS005933
20 µg, 100 µg

RBL1 Overview

Facts about Retinoblastoma-like protein 1.

RBL1 3D structure. Source: alphafold

Retinoblastoma-like protein 1 (RBL1)

Key regulator of entry into mobile division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.

Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys- 20' trimethylation.

Gene Information

Human
Gene Name:	RBL1
Uniprot:	P28749
Entrez:	5933

Family

Belongs to:

retinoblastoma protein (RB) family

Alternative Names

cellular protein 107,107 kDa retinoblastoma-associated protein; cp107; p107MGC40006; PRB1; retinoblastoma-like 1 (p107); retinoblastoma-like protein 1

Molecular Weight

Mass (kDA):
120.847 kDA

Genomic Context


Human

Location:	20q11.23
Sequence:	20; NC_000020.11 (36996349..37096029, complement)

Subcellular Localizations

Nucleus.

Diseases

Retinoblastoma
Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Growth Arrest
Hyperplasia
Growth Retardation
Osteosarcoma
Carcinogenesis
Lymphoma
Uterine Cervical Neoplasm
Metaplastic Cell Transformation

Malignant Paraganglionic Neoplasm
Malignant Tumor Of Cervix
Leukemia
Burkitt Lymphoma
Cytomegalovirus Infections
Dysplasia
Prostatic Neoplasms

Interacting Proteins

BEGAIN
CDK4
DYRK1A
DYRK1B
FOXO3

IRF3
Pax3
PPP2CA
Sirt1

Pathways

Cell Cycle
Cell Proliferation
S Phase
Cell Growth
Cell Cycle Arrest
G1 Phase
Localization
Senescence
Dna Replication
Cell Differentiation
Hyperphosphorylation
Mitosis
Cell Division

Methylation
Cell Death
Regulation Of Cell Proliferation
Pathogenesis
Proteolysis
Chondrocyte Proliferation
Regeneration

PTMs

Phosphorylation
Dephosphorylation
Acetylation
Methylation

Cleavage
Reduction
Phosphorothioation
Ubiquitination

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RBL1

References

PMID: 8319904 by Zhu L., et al. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

PMID: 1833063 by Ewen M.E., et al. Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein.