RNA-binding protein 7 (RBM7)

Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei.

Substrate targeting is facilitated by its cofactor MTREX, which joins to RNA-binding protein adapters (PubMed:27871484). Potential involved in germ cell RNA processing and meiosis (Probable).