RCC1L Antibodies

AND RCC1L ELISA kits, RCC1L Proteins

Many biological assays use antibodies to detect RCC1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RCC1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RCC1L antibodies...

We validate the specificity of these antibodies to RCC1L by testing them on tissues known to express RCC1L positively and negatively. Browse below to find the RCC1L antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: TRIM11

RCC1L Infographic by Boster Bio

All RCC1L Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

RCC1L Overview

Facts about RCC1-like G exchanging factor-like protein.

RCC1L 3D structure. Source: alphafold

RCC1-like G exchanging factor-like protein (RCC1L)

Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1- dependent mitochondrial fusion (PubMed:28746876).

Plays an important role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is needed for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system (PubMed:27667664).

Gene Information

Human
Gene Name:	RCC1L
Uniprot:	Q96I51
Entrez:	81554

Family

Belongs to:

No superfamily

Alternative Names

RCC1-like G exchanging factor-like protein

Molecular Weight

Mass (kDA):
49.997 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (75027119..75073881, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Mitochondrion membrane. Mitochondrion inner membrane.

Interacting Proteins

NME6

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RCC1L

References

PMID: 12073013 by Merla G., et al. Identification of additional transcripts in the Williams-Beuren syndrome critical region.

PMID: 27667664 by Arroyo J.D., et al. A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.