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- Table of Contents
REC8 Antibodies
AND REC8 ELISA kits, REC8 Proteins
Many biological assays use antibodies to detect REC8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with REC8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop REC8 antibodies...
Designing a Western blot for REC8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the REC8 Western Blot GuideDesigning an IHC experiment for REC8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the REC8 IHC GuideREC8 Infographic by Boster Bio
All REC8 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A04934-2
100 μg/vial
Cat # A04934-2
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04942-3
100 μg/vial
Cat # A04942-3
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04915-2
100 μg/vial
Cat # A04915-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04921-1
100 μg/vial
Cat # A04921-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04941-1
100 μg/vial
Cat # A04941-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04917-2
100 µg/vial
Cat # A04917-2
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # A04926-1
100 μg/vial
Cat # A04926-1
100 μg/vial
REC8 Overview
Facts about Meiotic recombination protein REC8 homolog.
Meiotic recombination protein REC8 homolog (REC8)
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin through anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | REC8 |
| Uniprot: | O95072 |
| Entrez: | 9985 |
Family
| Belongs to: |
|---|
| rad21 family |
Alternative Names
Cohesin Rec8p; cohesion rec8p; HR21spB; meiotic recombination and sister chromatid cohesion phosphoprotein of therad21p family; meiotic recombination protein REC8 homolog; meiotic recombination protein REC8-like 1; MGC950; REC8 homolog (yeast); REC8L1human homolog of rad21, S. pombe; REC8-like 1 (yeast); REC8-like 1; Rec8p; recombination and sister chromatid cohesion protein homolog
Molecular Weight
Mass (kDA):
62.614 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q12 |
| Sequence: | 14; NC_000014.9 (24171931..24180408) |
Tissue Specificity
Expressed in testis and thymus. Expressed in the B-cell lines WI-L2-NS and Namalwa (at protein level).
Subcellular Localizations
Nucleus. Chromosome. Chromosome, centromere. In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localised to centromeres and spindle poles in endopolyploid tumor cells.
Diseases
- Aneuploidy
- Infertility
- Sterility
- Neoplasms
- Male Infertility
- Cell Invasion
- Azoospermia
- Chromosome Breakage
- Cytogenetic Abnormality
- Congenital Abnormality
- Polyploidy
Pathways
- Meiosis
- Chromosome Segregation
- Meiosis I
- Prophase
- Sister Chromatid Cohesion
- Mitosis
- Anaphase
- Metaphase
- Meiosis Ii
- Localization
- Pachytene
- Dna Replication
- S Phase
PTMs
- Cleavage
- Phosphorylation
- Dephosphorylation
Research Areas
- Cell Cycle and Replication
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REC8
bosterbio.com/bosterbio-gene-info-cards/REC8
References
PMID: 10207075 by Parisi S., et al. Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans.
1 Publications of Boster REC8 Antibodies & ELISA Kits
- PubMed ID: -, Matthew D. Regan,Edna Chiang,Yunxi Liu,Marco Tonelli,Kristen M. Verdoorn,Sadie R...
*More publications can be found for each product on its corresponding product page