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- Table of Contents
Facts about Regenerating islet-derived protein 3-gamma.
The uncleaved form has bacteriostatic action, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.
Mouse | |
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Gene Name: | Reg3g |
Uniprot: | O09049 |
Entrez: | 19695 |
Belongs to: |
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No superfamily |
Regenerating islet-derived protein 3-gamma
Mass (kDA):
19.307 kDA
Mouse | |
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Location: | 6|6 C3 |
Sequence: | 6; |
Predominantly expressed in the small intestine, including Paneth cells (at protein level). Hardly detectable in the colon (at protein level). Highly expressed in the lung epithelium during methicillin-resistant S.aureus infection (at protein level). Skin injury increases its epidermal expression. Also expressed in the pancreas.
PMID: 9055810 by Narushima Y., et al. Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma.
PMID: 19095652 by Mukherjee S., et al. Regulation of C-type lectin antimicrobial activity by a flexible N- terminal prosegment.