Renin-1 Antibodies

AND Ren1 ELISA kits, Renin-1 Proteins

Many biological assays use antibodies to detect Renin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Renin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Renin-1 antibodies...

We validate the specificity of these antibodies to Renin-1 by testing them on tissues known to express Ren1 positively and negatively. Browse below to find the Ren1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ren1 Infographic by Boster Bio

All Ren1 Products

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Mouse Renin 1/Ren1 ELISA Kit PicoKine®

1 Citations 7 Q&As

Mouse

ELISA

$499
Cat # EK1250
96 wells/kit, with removable strips.

Mouse Renin Recombinant Protein

SDS-PAGE

$293
Cat # PROTP06281
Starting from 4ug

Ren1 Overview

Facts about Renin-1.

Ren1 3D structure. Source: alphafold

Renin-1 (Ren1)

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. .

Gene Information

Mouse
Gene Name:	Ren1
Uniprot:	P06281
Entrez:	19701

Family

Belongs to:

peptidase A1 family

Alternative Names

angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; HNFJ2; REN; renin precursor, renal; Renin

Molecular Weight

Mass (kDA):
44.343 kDA

Genomic Context


Mouse

Location:	1 E4\|1 57.91 cM
Sequence:	1;

Tissue Specificity

Kidney.

Diseases

Hypertensive Disease
Neoplasms
Malignant Neoplasms
Mesothelioma
Malignant Paraganglionic Neoplasm
Kidney Diseases
Essential Hypertension
Malignant Mesothelioma
Cell Transformation, Neoplastic
Pleural Neoplasms
Hypertrophy
Medulloblastoma
Hemorrhage

Carcinoma
Nervousness
Pleural Mesothelioma
Malignant Pleural Mesothelioma
Dysequilibrium Syndrome
Cardiovascular Diseases
Malignant Neoplasm Of Breast

Pathways

Pathogenesis
Localization
Secretion
Transport
Cell Proliferation
Excretion
Cell Death
Oncogenesis
Glycosylation
Ovulation
Aging
Translation
Proprioception

Vasodilation
Detection Of Glucose
Ossification
Tropism
Reflex
Cell Differentiation
Chromatin Remodeling

PTMs

Cleavage
Phosphorylation
Ubiquitination
Glycosylation
Deacetylation
Acetylation

Oxidation
Methylation
Dephosphorylation
Biotinylation
Reduction
Deglycosylation

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ren1

References

PMID: 6370686 by Holm I., et al. Evolution of aspartyl proteases by gene duplication: the mouse renin gene is organized in two homologous clusters of four exons.

PMID: 2685761 by Kim W.S., et al. Nucleotide sequence of a cDNA coding for mouse Ren1 preprorenin.