Raftlin-2 Antibodies

AND Rftn2 ELISA kits, Raftlin-2 Proteins

Many biological assays use antibodies to detect Raftlin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Raftlin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Raftlin-2 antibodies...

We validate the specificity of these antibodies to Raftlin-2 by testing them on tissues known to express Rftn2 positively and negatively. Browse below to find the Rftn2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Rftn2 Infographic by Boster Bio

All Rftn2 Products

Product

Figures

Specificity

Applications

Price

Anti-Raftlin-2 RFTN2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A17009
100ul

RFTN2 (NM_144629) Human Recombinant Protein

$1249
Cat # PROTQ52LD8
20 µg

RFTN2 (NM_144629) Human Over-expression Lysate

Human

$628
Cat # LS130132
100 µg

Rftn2 Overview

Facts about Raftlin-2.

Raftlin-2 (Rftn2)

Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and following IFNB1 production (PubMed:27022195). May regulate B-cell antigen receptor-mediated signaling.

Gene Information

Mouse
Gene Name:	Rftn2
Uniprot:	Q8CHX7
Entrez:	74013

Family

Belongs to:

raftlin family

Alternative Names

C2orf11; chromosome 2 open reading frame 11; FLJ30574; MGC117313; raftlin family member 2; Raftlin-2; Raft-linking protein 2

Molecular Weight

Mass (kDA):
54.972 kDA

Genomic Context


Mouse

Location:	1\|1 C1.2
Sequence:	1;

Tissue Specificity

Expressed in B-cells, heart, brain, spleen, large intestine and lung (PubMed:19414744). Expressed in dendritic cells and macrophages (PubMed:27022195).

Pathways

Endoderm Formation
Gastrulation

PTMs

Lipoprotein
Myristate

Palmitate
Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rftn2

References

PMID: 19414744 by Saeki K., et al. A major lipid raft protein raftlin modulates T cell receptor signaling and enhances th17-mediated autoimmune responses.

PMID: 27022195 by Tatematsu M., et al. Raftlin controls lipopolysaccharide-induced TLR4 internalization and TICAM-1 signaling in a cell type-specific manner.