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- Table of Contents
RFX1 Antibodies
AND RFX1 ELISA kits, RFX1 Proteins
Many biological assays use antibodies to detect RFX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RFX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RFX1 antibodies...
Designing an IHC experiment for RFX1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RFX1 IHC GuideRFX1 Infographic by Boster Bio
All RFX1 Products
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RFX1 Overview
Facts about MHC class II regulatory factor RFX1.
MHC class II regulatory factor RFX1 (RFX1)
Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes.
Also binds to an inverted repeat (ENH1) necessary for hepatitis B virus genes expression and into the most upstream element (alpha) of the RPL30 promoter. .
Gene Information
| Human | |
|---|---|
| Gene Name: | RFX1 |
| Uniprot: | P22670 |
| Entrez: | 5989 |
Family
| Belongs to: |
|---|
| RFX family |
Alternative Names
EFC; EF-C; Enhancer factor C; MHC class II regulatory factor RFX; MHC class II regulatory factor RFX1; Regulatory factor X 1; regulatory factor X, 1 (influences HLA class II expression); RFX; trans-acting regulatory factor 1; Transcription factor RFX1
Molecular Weight
Mass (kDA):
104.758 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.12 |
| Sequence: | 19; NC_000019.10 (13961530..14007514, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Hepatitis B
- Hepatitis
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Mycoplasma Pneumonia
- Glioma
- Nervousness
- Carcinoma
- Cell Transformation, Neoplastic
- Glioblastoma
- Malignant Tumor Of Cervix
- Immunologic Deficiency Syndromes
Interacting Proteins
- FOXN2
Pathways
- Methylation
- Cell Cycle
- Dna Methylation
- Dna Replication
- Rna Interference
- Localization
- Transport
- Neurogenesis
- Regulation Of Gene Expression
- Spermatogenesis
- Cell Differentiation
- Meiosis
- Cell Proliferation
PTMs
- Methylation
- Acetylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFX1
bosterbio.com/bosterbio-gene-info-cards/RFX1
References
PMID: 2253877 by Reith W., et al. MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.
PMID: 8413236 by Siegrist C.A., et al. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer.