RHBDL2 Antibodies

AND RHBDL2 ELISA kits, RHBDL2 Proteins

Many biological assays use antibodies to detect RHBDL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHBDL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHBDL2 antibodies...

We validate the specificity of these antibodies to RHBDL2 by testing them on tissues known to express RHBDL2 positively and negatively. Browse below to find the RHBDL2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RHBDL2 Infographic by Boster Bio

All RHBDL2 Products

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Product

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Specificity

Applications

Price

RHBDL2 (NM_017821) Human Over-expression Lysate

Human

$628
Cat # LS054933
20 µg, 100 µg

Anti-RHBDL2 Antibody

Human

ELISA, WB

$370
Cat # A10287
100 μl/vial

RHBDL2 Overview

Facts about Rhomboid-related protein 2.

RHBDL2 3D structure. Source: alphafold

Rhomboid-related protein 2 (RHBDL2)

Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.

Gene Information

Human
Gene Name:	RHBDL2
Uniprot:	Q9NX52
Entrez:	54933

Family

Belongs to:

peptidase S54 family

Alternative Names

EC 3.4.21.105; FLJ20435; MGC16997; rhomboid (veinlet, Drosophila)-like 2; rhomboid protease 2; rhomboid, veinlet-like 2 (Drosophila); Rhomboid-like protein 2; rhomboid-related protein 2; RRP2

Molecular Weight

Mass (kDA):
34.021 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (38885807..38941830, complement)

Subcellular Localizations

[Rhomboid-related protein 2, C-terminal fragment]: Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Myeloproliferative Syndrome, Transient
Malignant Squamous Cell Neoplasm
Palmoplantar Keratosis
Pain
Esophageal Neoplasms

Keratoderma, Palmoplantar, Diffuse
Carcinoma

Pathways

Wound Healing
Localization
Secretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHBDL2

References

PMID: 11672525 by Urban S., et al. Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases.

PMID: 15047175 by Pascall J.C., et al. Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2.