RHCG Antibodies

AND RHCG ELISA kits, RHCG Proteins

Many biological assays use antibodies to detect RHCG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHCG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHCG antibodies...

We validate the specificity of these antibodies to RHCG by testing them on tissues known to express RHCG positively and negatively. Browse below to find the RHCG antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for RHCG? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RHCG IHC Guide

RHCG Infographic by Boster Bio

All RHCG Products

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Applications

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Anti-Ammonium transporter Rh type C RhCG Antibody

Western Blot analysis of extracts from Jurkat, K562 cells, using RhCG Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A03655
100ul

RHCG (NM_016321) Human Over-expression Lysate

Human

$628
Cat # LS051458
20 µg, 100 µg

RHCG Overview

Facts about Ammonium transporter Rh type C.

RHCG 3D structure. Source: alphafold

Ammonium transporter Rh type C (RHCG)

Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.

Gene Information

Human
Gene Name:	RHCG
Uniprot:	Q9UBD6
Entrez:	51458

Family

Belongs to:

ammonium transporter (TC 2.A.49) family

Alternative Names

ammonium transporter Rh type C; CDRC2; chromosome 15 open reading frame 6; PDRC2C15orf6; Rh family type C glycoprotein; Rh family, C glycoprotein; Rh glycoprotein kidney; Rh type C glycoprotein; Rhesus blood group family type C glycoprotein; Rhesus blood group, C glycoprotein; RHGKTumor-related protein DRC2; SLC42A3

Molecular Weight

Mass (kDA):
53.179 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (89471407..89496583, complement)

Tissue Specificity

Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney.

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Also detected at the basolateral membrane and in subapical vesicles.

Diseases

Acidosis
Metabolic Acidosis
Renal Tubular Acidosis
Disease Of Adrenal Medulla
Rheumatic Heart Disease
Carcinoma
Malignant Neoplasms
Malignant Squamous Cell Neoplasm
Alkalosis
Esophageal Neoplasms
Renal Tubular Acidosis, Type I
Kidney Diseases
Metabolic Alkalosis

Kidney Neoplasm
Macular Corneal Dystrophy Type I
Injury To Kidney
Chromophobe Renal Cell Carcinoma
Neoplasms
Oncocytic Neoplasm
Renal Cell Carcinoma

Pathways

Transport
Excretion
Ammonium Transport
Secretion
Localization
Ion Transport
Translation
Keratinization
Transmembrane Transport
Membrane Hyperpolarization
Cell Development
Neurogenesis
Pseudohyphal Growth

Keratinocyte Differentiation
Gas Transport
Glomerular Filtration
Regeneration
Chemotaxis
Extracellular Matrix Organization
Response To Hydrogen Peroxide

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHCG

References

PMID: 10852913 by Liu Z., et al. Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.

PMID: 12204676 by Chen B.-S., et al. RhCG is downregulated in oesophageal squamous cell carcinomas, but expressed in multiple squamous epithelia.