RHOT2 Antibodies

AND RHOT2 ELISA kits, RHOT2 Proteins

Many biological assays use antibodies to detect RHOT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHOT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHOT2 antibodies...

We validate the specificity of these antibodies to RHOT2 by testing them on tissues known to express RHOT2 positively and negatively. Browse below to find the RHOT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for RHOT2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RHOT2 IHC Guide

RHOT2 Infographic by Boster Bio

All RHOT2 Products

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Product

Figures

Specificity

Applications

Price

Anti-MIRO2/RHOT2 Antibody Picoband®

Western blot analysis of MIRO2/RHOT2 using anti-MIRO2/RHOT2 antibody (A08801-1)

IHC analysis of MIRO2/RHOT2 using anti-MIRO2/RHOT2 antibody (A08801-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A08801-1
100 μg/vial

MIRO2 (RHOT2) (NM_138769) Human Over-expression Lysate

Human

$628
Cat # LS089941
20 µg, 100 µg

RHOT2 Overview

Facts about Mitochondrial Rho GTPase 2.

RHOT2 3D structure. Source: alphafold

Mitochondrial Rho GTPase 2 (RHOT2)

Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).

Gene Information

Human
Gene Name:	RHOT2
Uniprot:	Q8IXI1
Entrez:	89941

Family

Belongs to:

mitochondrial Rho GTPase family

Alternative Names

ARHT2; C16orf39; chromosome 16 open reading frame 39; EC 3.6.5; EC 3.6.5.-; hMiro-2; MIRO-2mitochondrial Rho 2; mitochondrial Rho GTPase 2; Ras homolog gene family member T2; ras homolog gene family, member T2; RASL

Molecular Weight

Mass (kDA):
68.118 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (668083..674174)

Tissue Specificity

Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Mitochondrion outer membrane; Single-pass type IV membrane protein. Colocalizes with MGARP and RHOT2 at the mitochondria.

Diseases

Parkinson Disease
Optic Atrophy
Hereditary Diseases
Charcot-marie-tooth Disease
Nervousness
Neurodegenerative Disorders
Optic Atrophy, Autosomal Dominant
Atrophy

Hypoxia
Anoxia

Interacting Proteins

TRAK1

Pathways

Transport
Mitochondrial Transport
Mitochondrial Fusion
Microtubule-based Transport

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOT2

References

PMID: 12482879 by Fransson A., et al. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.

PMID: 15218247 by Shan Y., et al. Cloning and characterization of the mouse Arht2 gene which encodes a putative atypical GTPase.