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Ras and Rab interactor 3 Antibodies

AND RIN3 ELISA kits, Ras and Rab interactor 3 Proteins

Many biological assays use antibodies to detect Ras and Rab interactor 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ras and Rab interactor 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ras and Rab interactor 3 antibodies...

We validate the specificity of these antibodies to Ras and Rab interactor 3 by testing them on tissues known to express RIN3 positively and negatively. Browse below to find the RIN3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIN3 Infographic by Boster Bio

RIN3 protein infographic

All RIN3 Products

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RIN3 (NM_024832) Human Recombinant Protein

Coomassie blue staining of purified RIN3 protein

Coomassie blue staining of purified RIN3 protein

$1062
Cat # PROTQ8TB24
20 µg

RIN3 (NM_024832) Human Over-expression Lysate

RIN3 Human Over-expression Lysates NM_024832

RIN3 Human Over-expression Lysates NM_024832

Human

$960
Cat # LS079890
20 µg, 100 µg

RIN3 Overview

Facts about Ras and Rab interactor 3.

RIN3 3D structure

RIN3 3D structure. Source: alphafold

Ras and Rab interactor 3 (RIN3)

Ras effector protein that acts as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.

.

Gene Information

Human
Gene Name:	RIN3
Uniprot:	Q8TB24
Entrez:	79890

Gene Information

Family

Belongs to:

RIN (Ras interaction/interference) family

Family

Alternative Names

DKFZp762H1613; FLJ11700; FLJ22439; RAB5 interacting protein 3; Ras and Rab interactor 3; Ras interaction/interference protein 3

Molecular Weight

Mass (kDA):
107.854 kDA

Molecular Weight

Genomic Context


Human

Location:	14q32.12
Sequence:	14; NC_000014.9 (92513773..92688994)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cytoplasm. Cytoplasmic vesicle. Early endosome. Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles.

Subcellular Localization

Diseases

Osteitis Deformans
Bone Diseases
Osteosarcoma
Malignant Neoplasms
Anemia
Pituitary Diseases
Anemia, Sickle Cell
Osteoporosis

Mastocytosis
Metabolic Bone Disorder

Disease

Interacting Proteins

CRK
NCK1
PLCG1

Interacting Proteins

Pathways

Bone Remodeling
Endocytosis
Membrane Budding
Localization
Transport
Receptor-mediated Endocytosis
Cell Migration

Pathogenesis
Autophagy

Pathways

PTMs

Phosphorylation

Research Areas

Signal Transduction

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIN3

References

PMID: 12972505 by Kajiho H., et al. RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway.

PMID: 11733506 by Saito K., et al. A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5.