RNF123 Antibodies

AND RNF123 ELISA kits, RNF123 Proteins

Many biological assays use antibodies to detect RNF123, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF123 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF123 antibodies...

We validate the specificity of these antibodies to RNF123 by testing them on tissues known to express RNF123 positively and negatively. Browse below to find the RNF123 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for RNF123? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the RNF123 Western Blot Guide

Designing an IHC experiment for RNF123? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RNF123 IHC Guide

RNF123 Infographic by Boster Bio

All RNF123 Products

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Product

Figures

Specificity

Applications

Price

Anti-RNF123 Antibody Picoband®

1 Citations

IHC analysis of RNF123 using anti-RNF123 antibody (A09642-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A09642-1
100 μg/vial

RNF123 (NM_022064) Human Over-expression Lysate

Human

$960
Cat # LS063891
20 µg, 100 µg

RNF123 Overview

Facts about E3 ubiquitin-protein ligase RNF123.

RNF123 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF123 (RNF123)

Catalytic subunit of the KPC complex that functions as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.

Gene Information

Human
Gene Name:	RNF123
Uniprot:	Q5XPI4
Entrez:	63891

Family

Belongs to:

No superfamily

Alternative Names

DKFZp686C2222; E3 ubiquitin-protein ligase RNF123; EC 6.3.2.-; FLJ12565; Kip1 ubiquitination-promoting complex protein 1; KPC1; ring finger protein 123MGC163504; ubiquitin ligase

Molecular Weight

Mass (kDA):
148.515 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (49688753..49721529)

Subcellular Localizations

Cytoplasm.

Diseases

Major Depressive Disorder
Retinoblastoma
Depressive Disorder
Cognition Disorders
Recurrent Major Depressive Episodes

Pathways

Nuclear Export
Cell Cycle
G1 Phase
Proteolysis
Rna Interference

PTMs

Ubiquitination

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF123

References

PMID: 15531880 by Kamura T., et al. Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.

PMID: 16227581 by Hara T., et al. Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.