RNF130 Antibodies

AND RNF130 ELISA kits, RNF130 Proteins

Many biological assays use antibodies to detect RNF130, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF130 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF130 antibodies...

We validate the specificity of these antibodies to RNF130 by testing them on tissues known to express RNF130 positively and negatively. Browse below to find the RNF130 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF130 Infographic by Boster Bio

All RNF130 Products

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Anti-RNF130 Antibody

3 Q&As

Western Blot (WB) analysis of specific cells using RNF130 Polyclonal antibody

Human, Mouse, Rat

ELISA, IHC, WB

$399
Cat # A12501
100μl

RNF130 (NM_018434) Human Over-expression Lysate

Human

$628
Cat # LS055819
20 µg, 100 µg

RNF130 Overview

Facts about E3 ubiquitin-protein ligase RNF130.

RNF130 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF130 (RNF130)

May have a function during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin- protein ligase.

Gene Information

Human
Gene Name:	RNF130
Uniprot:	Q86XS8
Entrez:	55819

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase RNF130; EC 2.1.1; EC 6.3.2; EC 6.3.2.-; g1-related zinc finger protein; G1RZFP; Goliath homolog; GOLIATH; GP; H-Goliath; MGC117241; MGC99542; ring finger protein 130MGC138647

Molecular Weight

Mass (kDA):
46.405 kDA

Genomic Context


Human

Location:	5q35.3
Sequence:	5; NC_000005.10 (179911651..180071759, complement)

Tissue Specificity

Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cytoplasm.

Diseases

Cell Transformation, Neoplastic
Gestational Trophoblastic Neoplasms
Neoplasms
Complete Hydatidiform Mole
Hydatidiform Mole
Leukemia

Pathways

Mesoderm Formation
Pathogenesis
Localization

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF130

References

PMID: 13679316 by Guais A., et al. Goliath, a ring-H2 mitochondrial protein, regulated by luteinizing hormone/human chorionic gonadotropin in rat Leydig cells.

PMID: 16549277 by Guais A., et al. h-Goliath, paralog of GRAIL, is a new E3 ligase protein, expressed in human leukocytes.