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- Table of Contents
Facts about E3 ubiquitin-protein ligase RNF165.
Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL (PubMed:23610558). .
| Mouse | |
|---|---|
| Gene Name: | Rnf165 |
| Uniprot: | E9QAU8 |
| Entrez: | 225743 |

| Belongs to: |
|---|
| Arkadia family |

ARKL2; ring finger protein 165
Mass (kDA):
39.736 kDA

| Mouse | |
|---|---|
| Location: | 18|18 E3 |
| Sequence: | 18; |
Expressed in neurons of the nervous system.

PMID: 23610558 by Kelly C.E., et al. Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.