Rnf169 Antibodies

AND Rnf169 ELISA kits, Rnf169 Proteins

Many biological assays use antibodies to detect Rnf169, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rnf169 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rnf169 antibodies...

We validate the specificity of these antibodies to Rnf169 by testing them on tissues known to express Rnf169 positively and negatively. Browse below to find the Rnf169 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Rnf169 Infographic by Boster Bio

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Anti-RNF169 Antibody Picoband®

6 Q&As

Western blot analysis of RNF169 using anti-RNF169 antibody (A10407-1)

IHC analysis of RNF169 using anti-RNF169 antibody (A10407-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A10407-1
100 μg/vial

Rnf169 Overview

Facts about E3 ubiquitin-protein ligase RNF169.

E3 ubiquitin-protein ligase RNF169 (Rnf169)

Probable E3 ubiquitin-protein ligase that functions as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thus acting as a negative regulator of DSBs repair.

E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair. .

Gene Information

Mouse
Gene Name:	Rnf169
Uniprot:	E9Q7F2
Entrez:	108937

Family

Belongs to:

RNF169 family

Alternative Names

EC 3.4.24.57; KIAA1991EC 3.1.4.16; ring finger protein 169

Molecular Weight

Mass (kDA):
75.796 kDA

Genomic Context


Mouse

Location:	7\|7 E2
Sequence:	7;

Diseases

Genomic Instability

Pathways

Dna Repair

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rnf169

References

PMID: 19468303 by Church D.M., et al. Lineage-specific biology revealed by a finished genome assembly of the mouse.

PMID: 15368895 by Okazaki N., et al. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.