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- Table of Contents
Facts about Rab effector Noc2.
.
Human | |
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Gene Name: | RPH3AL |
Uniprot: | Q9UNE2 |
Entrez: | 9501 |
Belongs to: |
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No superfamily |
Noc2; NOC2No C2 domains protein; rab effector Noc2; rabphilin 3A-like (without C2 domains); Rabphilin-3A-like protein
Mass (kDA):
34.464 kDA
Human | |
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Location: | 17p13.3 |
Sequence: | 17; NC_000017.11 (212389..352842, complement) |
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
PMID: 10395805 by Smith J.S., et al. Cloning of a human ortholog (RPH3AL) of (RNO)Rph3al from a candidate 17p13.3 medulloblastoma tumor suppressor locus.
PMID: 15003533 by Manabe S., et al. Identification and characterization of Noc2 as a potential Rab3B effector protein in epithelial cells.