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- Table of Contents
Facts about 60S ribosomal protein L10.
May play a role in the embryonic brain development (PubMed:25316788). .
Human | |
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Gene Name: | RPL10 |
Uniprot: | P27635 |
Entrez: | 6134 |
Belongs to: |
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universal ribosomal protein uL16 family |
60S ribosomal protein L10; DXS648EFLJ27072; DXS648FLJ23544; Laminin receptor homolog; NOV; Protein QM; QMDKFZp686J1851; ribosomal protein L10; Tumor suppressor QM; Wilms tumor-related protein
Mass (kDA):
24.604 kDA
Human | |
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Location: | Xq28 |
Sequence: | X; NC_000023.11 (154398065..154402339) |
What Are the Best Uses of the RPL10 Marker? Continue reading to learn more. This new marker for listeria bacteria FSL M6-0635 (SEQID NO.) will help you understand the best uses and benefits of it. 1088 & 1092).
It is unknown what the RPL10 genes function is. The majority of research on autism has been done so far. However, the gene may also have an important role in T–ALLs. Exome sequencing analyses have identified mutations in RPL5 and RPL10 in pediatric T-ALLs. T-ALLs have been linked to RPL10's mutation Arg98. Other tumors may also carry mutations in RPL5 or RPL10, but it is not known if this relationship exists.
A RPL10R98S mutation in CHO–S cells could increase protein production. The vector design may be altered depending on the type of protein being produced. Two-fold increase in eGFP expression was observed in CHOS cells after knock-in RPL10-R98S. Monoclonal antibodies were not affected by RPL10-R98S knock-in.
RPL5 and RPL10 mutations are promising diagnostic tools in AT/RT. The genes have high-sensitivity, specificity, and were found to be useful diagnostic tools for AT/RT. However more research is needed to understand the roles of these genes in these disorders. One study, carried out by Beckwith JB and Haas JE, focused on malignant rhabdoid tumors in children and RPL10-mutated rhabdoid cell carcinomas in adults.
By neutralizing oxidative stress, RPL10-R98S mutant mice produce more proteins. Restoring mitochondrial function can be achieved by neutralizing oxidative Stress. Further research will identify additional RPL10/R98S genotypes that could be used to improve therapeutic results. This study was supported with other research and publications, and has received a high citation score. The RPL10R98S mutant is highly suitable for therapeutic research.
RPL10-mutant RBOsomal Gene has been linked in a variety diseases, including cancers and leukemias. Enhanced BCL-2 translation in RPL10-mutant T-ALL may be a new therapeutic target. This is not all. Other benefits of the RPL10 mutant marker include a shorter treatment course and improved prognosis.
The RPL10 is one of the most commonly used proteins in biology, which is why Boster Bio created an antibody for it. Boster Bio's anti RPL10L antibody reacts against the Human RPL10 protein. It is suitable for immunofluorescence and IHC as well as WB applications. It reacts with many samples, including human cells and eukaryotic cells.
The bacterial strains that can be detected by this antigen include the Carnobacterium gallinarum DSM 4847, the Opitutaceae bacterium TAV5, and the Listeria bacterium NK4A144. These bacterial species can be detected by the antigen in the blood or urine.
PMID: 1658743 by Dowdy S.F., et al. The isolation and characterization of a novel cDNA demonstrating an altered mRNA level in nontumorigenic Wilms' microcell hybrid cells.
PMID: 1303197 by van den Ouweland A.M.W., et al. Identification and characterization of a new gene in the human Xq28 region.