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- Table of Contents
Designing an IHC experiment for RSRC1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RSRC1 IHC GuideFacts about Serine/Arginine-related protein 53.
May have a role in the recognition of the 3' splice site during the second step of splicing. .
| Human | |
|---|---|
| Gene Name: | RSRC1 |
| Uniprot: | Q96IZ7 |
| Entrez: | 51319 |

| Belongs to: |
|---|
| No superfamily |

arginine/serine-rich 21; arginine/serine-rich coiled-coil 1
Mass (kDA):
38.677 kDA

| Human | |
|---|---|
| Location: | 3q25.32 |
| Sequence: | 3; NC_000003.12 (158110052..158545730) |
Nucleus. Nucleus speckle. Cytoplasm. Shuttles between the nucleus and cytoplasm.




PMID: 15798186 by Cazalla D., et al. A novel SR-related protein is required for the second step of pre- mRNA splicing.
PMID: 29522154 by Perez Y., et al. RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3.