E3 ubiquitin-protein ligase RNF170 (Rnf170)

E3 ubiquitin-protein ligase which plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation through the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.

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