Rnf19b Antibodies

AND Rnf19b ELISA kits, Rnf19b Proteins

Many biological assays use antibodies to detect Rnf19b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rnf19b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rnf19b antibodies...

We validate the specificity of these antibodies to Rnf19b by testing them on tissues known to express Rnf19b positively and negatively. Browse below to find the Rnf19b antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Rnf19b Infographic by Boster Bio

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Rnf19b Overview

Facts about E3 ubiquitin-protein ligase RNF19B.

E3 ubiquitin-protein ligase RNF19B (Rnf19b)

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Protects against staurosporin-induced cell death (By similarity). .

Gene Information

Mouse
Gene Name:	Rnf19b
Uniprot:	A2A7Q9
Entrez:	75234

Family

Belongs to:

RBR family

Alternative Names

IBRDC3; NKLAM; RNF19B ring finger protein 19B

Molecular Weight

Mass (kDA):
78.127 kDA

Genomic Context


Mouse

Location:	4\|4 D2.2
Sequence:	4;

Tissue Specificity

Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells (PubMed:10912506). Present in macrophages (at protein level) (PubMed:10912506). Ubiquitously expressed with high expression in testis (PubMed:27485036).

Diseases

Infective Disorder
Influenza
Osteoarthropathy
Headache
Osteoporosis
Influenza In Birds

Pathways

Osteoclast Differentiation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rnf19b

References

PMID: 10912506 by Portis T., et al. Gene structure of human and mouse NKLAM, a gene associated with cellular cytotoxicity.

PMID: 27485036 by Kaneko M., et al. Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation.