SAMD9 Antibodies

AND SAMD9 ELISA kits, SAMD9 Proteins

Many biological assays use antibodies to detect SAMD9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SAMD9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SAMD9 antibodies...

We validate the specificity of these antibodies to SAMD9 by testing them on tissues known to express SAMD9 positively and negatively. Browse below to find the SAMD9 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SAMD9 Infographic by Boster Bio

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SAMD9 Overview

Facts about Sterile alpha motif domain-containing protein 9.

SAMD9 3D structure. Source: alphafold

Sterile alpha motif domain-containing protein 9 (SAMD9)

May play a role in the inflammatory response to tissue injury and the management of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2.

May be involved in endosome fusion. .

Gene Information

Human
Gene Name:	SAMD9
Uniprot:	Q5K651
Entrez:	54809

Family

Belongs to:

No superfamily

Alternative Names

Sterile alpha motif domain-containing protein 9

Molecular Weight

Mass (kDA):
184.281 kDA

Genomic Context


Human

Location:	7q21.2
Sequence:	7; NC_000007.14 (93099513..93118023, complement)

Tissue Specificity

Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC).

Subcellular Localizations

Cytoplasm.

Interacting Proteins

EEA1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SAMD9

References

PMID: 17407603 by Li C.F., et al. Human sterile alpha motif domain 9, a novel gene identified as down- regulated in aggressive fibromatosis, is absent in the mouse.

PMID: 18094730 by Chefetz I., et al. Normophosphatemic familial tumoral calcinosis is caused by deleterious mutations in SAMD9, encoding a TNF-alpha responsive protein.