This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Acyl-CoA desaturase 1 Antibodies
AND Scd1 ELISA kits, Acyl-CoA desaturase 1 Proteins
Many biological assays use antibodies to detect Acyl-CoA desaturase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acyl-CoA desaturase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acyl-CoA desaturase 1 antibodies...
Previous: SEPTIN9
Next: Scg2
Scd1 Infographic by Boster Bio
All Scd1 Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M32769
100 μl/vial
Cat # M32769
100 μl/vial
Scd1 Overview
Facts about Acyl-CoA desaturase 1.
Acyl-CoA desaturase 1 (Scd1)
Stearyl-CoA desaturase that uses O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond in the Delta-9 place into fatty acyl-CoA substrates such as palmitoyl-CoA and stearoyl-CoA (PubMed:11500518, PubMed:11533264, PubMed:16275639, PubMed:16443825, PubMed:26098370).
Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:11500518, PubMed:11533264, PubMed:16443825, PubMed:26098370). Plays an essential role in lipid biosynthesis (PubMed:17127673, PubMed:10899171, PubMed:11500518, PubMed:11441127, PubMed:11533264, PubMed:12177411, PubMed:26098370).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Scd1 |
| Uniprot: | P13516 |
| Entrez: | 20249 |
Family
| Belongs to: |
|---|
| fatty acid desaturase type 1 family |
Alternative Names
FADS5; MSTP008; SCD1; SCD-1; SCDOS; Stearoyl-CoA desaturase
Molecular Weight
Mass (kDA):
41.046 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 19 C3|19 37.98 cM |
| Sequence: | 19; |
Tissue Specificity
Detected in liver (at protein level) (PubMed:10899171, PubMed:11533264). Detected in skin and liver (PubMed:10545940, PubMed:11161812, PubMed:11441127, PubMed:11533264). Detected in sebaceous gland, but not in hair follicle (PubMed:10545940). Detected in white and brown adipose tissue, eyelid, Harderian gland, and at lower levels in Meibomian gland, eyeball and adrenal gland (PubMed:11500518, PubMed:11533264). Highly expressed in liver, and detected at low levels in brain, heart, lung, stomach, skeletal muscle and kidney (PubMed:11161812, PubMed:12815040).
Diseases
- Anemia, Sickle Cell
- Sudden Cardiac Death
- Cardiac Death
- Cardiac Arrhythmia
- Infarction
- Pain
- Heart Diseases
- Anemia
- Myocardial Infarction
- Cerebrovascular Accident
- Cardiomyopathies
- Tachycardia, Ventricular
- Hypertensive Disease
Pathways
- Pathogenesis
- Dehiscence
- Coagulation
- Cell Adhesion
- Transport
- Secretion
- Glomerular Filtration
- Cell Cycle
- Fatty Acid Oxidation
- Lactation
- Cell Proliferation
- Aging
- Localization
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Methylation
- Nitration
- Deacetylation
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Scd1
bosterbio.com/bosterbio-gene-info-cards/Scd1
References
PMID: 2903162 by Ntambi J.M., et al. Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl- CoA desaturase.
PMID: 17738154 by Gates A.H., et al. Hereditary absence of sebaceous glands in the mouse.