Secretogranin-2 Antibodies

AND SCG2 ELISA kits, Secretogranin-2 Proteins

Many biological assays use antibodies to detect Secretogranin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Secretogranin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Secretogranin-2 antibodies...

We validate the specificity of these antibodies to Secretogranin-2 by testing them on tissues known to express SCG2 positively and negatively. Browse below to find the SCG2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCG2 Infographic by Boster Bio

All SCG2 Products

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Figures

Specificity

Applications

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Anti-Secretogranin-2 SCG2 Antibody

Western blot analysis of extracts of various cell lines, using SCG2 antibody at 1:1000 dilution

Immunofluorescence analysis of human pancreas cells using SCG2 Rabbit pAb at dilution of 1:100

Immunofluorescence analysis of rat pancreas cells using SCG2 Rabbit pAb at dilution of 1:100

Human, Rat

IF, ICC, WB

$405
Cat # A04779
100ul

Anti-Chromogranin C (SCG2) Mouse Monoclonal Antibody [Clone ID: OTI3F12]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SCG2 (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M04779
100 µl

Chromogranin C (SCG2) (NM_003469) Human Over-expression Lysate

Human

$628
Cat # LS007857
20 µg, 100 µg

Anti-Secretogranin II/SCG2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04779-2
100 μl/vial

SCG2 Overview

Facts about Secretogranin-2.

SCG2 3D structure. Source: alphafold

Secretogranin-2 (SCG2)

Secretogranin-2 is a neuroendocrine secretory granule protein, that's the precursor for biologically active peptides. .

Gene Information

Human
Gene Name:	SCG2
Uniprot:	P13521
Entrez:	7857

Family

Belongs to:

chromogranin/secretogranin protein family

Alternative Names

CHCG; Chromogranin-C; EM66; SCG2; secretogranin IICHGCchromogranin-C; secretoneurin; SgIIsecretogranin-2; SN

Molecular Weight

Mass (kDA):
70.941 kDA

Genomic Context


Human

Location:	2q36.1
Sequence:	2; NC_000002.12 (223596940..223602361, complement)

Subcellular Localizations

Secreted. Neuroendocrine and endocrine secretory granules.

Diseases

Neoplasms
Pituitary Diseases
Malignant Neoplasms
Endocrine Gland Neoplasms
Hypertensive Disease
Multiple Endocrine Neoplasia Type 1
Multiple Endocrine Neoplasia
Carcinoma
Tumor Angiogenesis
Pheochromocytoma
Adrenal Gland Neoplasms
Small Cell Carcinoma Of Lung
Nervousness

Neuroblastoma
Hereditary Malignant Neoplasm
Obesity
Neuroendocrine Tumors
Sclerosis
Classical Galactosemia
Adenoma

Interacting Proteins

ATRIP
UBQLN1

Pathways

Secretion
Secretory Pathway
Cell Differentiation
Regulated Secretory Pathway
Angiogenesis
Pathogenesis
Cell Adhesion
Insulin Secretion
Neurogenesis
Cellular Response To Nitrosative Stress
Protein Secretion
Ovulation
Localization

Neuroprotection
Oviposition
Reverse Transcription
Cell Communication
B Cell Differentiation
Exocytosis
Response To Nitrosative Stress

PTMs

Cleavage on pair of basic residues
Glycoprotein

Phosphoprotein
Sulfation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCG2

References

PMID: 2745426 by Gerdes H.-H., et al. The primary structure of human secretogranin II, a widespread tyrosine-sulfated secretory granule protein that exhibits low pH- and calcium-induced aggregation.

PMID: 9654353 by Leitner B., et al. Formation and sequence analysis of secretoneurin, a neuropeptide derived from secretogranin II, in mammalian, bird, reptile, amphibian and fish brains.