SCML2 Antibodies

AND SCML2 ELISA kits, SCML2 Proteins

Many biological assays use antibodies to detect SCML2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SCML2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SCML2 antibodies...

We validate the specificity of these antibodies to SCML2 by testing them on tissues known to express SCML2 positively and negatively. Browse below to find the SCML2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCML2 Infographic by Boster Bio

All SCML2 Products

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Product

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Specificity

Applications

Price

Anti-SCML2 Antibody

6 Q&As

Western Blot analysis of extracts from 293 cells, using SCML2 Polyclonal Antibody

Human

ELISA, IHC, WB

$399
Cat # A08958
100μl

Anti-SCML2 Mouse Monoclonal Antibody [Clone ID: OTI1E1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SCML2 (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M08958
100 µl

SCML2 (NM_006089) Human Over-expression Lysate

Human

$628
Cat # LS010389
20 µg, 100 µg

Anti-SCML2 Antibody Picoband®

Western blot analysis of SCML2 using anti-SCML2 antibody (A08958-1)

Flow Cytometry analysis of K562 cells using anti-SCML2 antibody (A08958-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08958-1
100 µg/vial

SCML2 Overview

Facts about Sex comb on midleg-like protein 2.

SCML2 3D structure. Source: alphafold

Sex comb on midleg-like protein 2 (SCML2)

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to keep the transcriptionally repressive state of homeotic genes throughout development (By similarity).

. .

Gene Information

Human
Gene Name:	SCML2
Uniprot:	Q9UQR0
Entrez:	10389

Family

Belongs to:

SCM family

Alternative Names

sex comb on midleg (Drosophila)-like 2; sex comb on midleg-like 2 (Drosophila); sex comb on midleg-like protein 2

Molecular Weight

Mass (kDA):
77.257 kDA

Genomic Context


Human

Location:	Xp22.13
Sequence:	X; NC_000023.11 (18239313..18355089, complement)

Tissue Specificity

Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasm Of Brain
Malignant Paraganglionic Neoplasm
Brain Neoplasms
Neoplasms
Congenital Abnormality
Rett Syndrome
Spasm
Tonic Convulsion
Muscle Hypotonia
Epilepsy
Leukemia, Myelocytic, Acute

Encephalopathies
Brain Diseases
Epilepsies, Myoclonic
Malignant Neoplasms
Myeloid Leukemia
Nance-horan Syndrome

Interacting Proteins

CDK2
CDKN1A
CDKN1B

Pathways

Methylation
Dna Methylation
Spermatogenesis
Chromatin Remodeling

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCML2

References

PMID: 10331946 by Montini E., et al. Identification of SCML2, a second human gene homologous to the Drosophila Sex comb on midleg (Scm): a new gene cluster on Xp22.

PMID: 12952983 by Sathyamurthy A., et al. Crystal structure of the malignant brain tumor (MBT) repeats in sex comb on midleg-like 2 (SCML2).