SCN7A Antibodies

AND SCN7A ELISA kits, SCN7A Proteins

Many biological assays use antibodies to detect SCN7A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SCN7A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SCN7A antibodies...

We validate the specificity of these antibodies to SCN7A by testing them on tissues known to express SCN7A positively and negatively. Browse below to find the SCN7A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCN7A Infographic by Boster Bio

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Anti-Na+ CP type VI alpha SCN7A Antibody

Human, Monkey

IHC, WB

$380
Cat # A09448-1
100ul

SCN7A Overview

Facts about Sodium channel protein type 7 subunit alpha.

SCN7A 3D structure. Source: alphafold

Sodium channel protein type 7 subunit alpha (SCN7A)

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

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Gene Information

Human
Gene Name:	SCN7A
Uniprot:	Q01118
Entrez:	6332

Family

Belongs to:

sodium channel (TC 1.A.1.10) family

Alternative Names

Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type VII subunit alpha; sodium channel, voltage-gated, type VI, alpha; sodium channel, voltage-gated, type VII, alpha polypeptide; sodium channel, voltage-gated, type VII, alpha; voltage-dependent sodium channel alpha subunit; voltage-gated, type VI, alpha polypeptide

Molecular Weight

Mass (kDA):
193.493 kDA

Genomic Context


Human

Location:	2q24.3
Sequence:	2; NC_000002.12 (166403573..166494264, complement)

Tissue Specificity

Heart and uterus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Nervousness
Dehydration
Sclerosis
Malignant Neoplasms
Epilepsy
Nervous System Disorder
Hypertensive Disease
Autoimmunity
Essential Hypernatremia
Disease Of Adrenal Medulla
Essential Hypertension
Neoplasm Metastasis
Malignant Bone Neoplasm

Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Sarcoma
Myxoid Cyst
Fibrosis
Neoplasms
Metastatic Malignant Neoplasm To The Bone

Pathways

Excretion
Localization
Water Homeostasis
Transport
Cell Adhesion
Smooth Muscle Contraction
Response To Camp
Aging
Peristalsis
Ion Transport
Muscle Contraction

Endocytosis
Diuresis
Mrna Transcription
Cell Death
Cell Cycle
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCN7A

References

PMID: 1317577 by George A.L. Jr., et al. Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.