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Protein sidekick-2 Antibodies
AND SDK2 ELISA kits, Protein sidekick-2 Proteins
Many biological assays use antibodies to detect Protein sidekick-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein sidekick-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein sidekick-2 antibodies...
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SDK2 Infographic by Boster Bio
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SDK2 Overview
Facts about Protein sidekick-2.
Protein sidekick-2 (SDK2)
Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs as well as the excitatory amacrine cells VG3-ACs.
Formation of synapses between both of these cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions.
Gene Information
| Human | |
|---|---|
| Gene Name: | SDK2 |
| Uniprot: | Q58EX2 |
| Entrez: | 54549 |
Family
| Belongs to: |
|---|
| sidekick family |
Alternative Names
Protein sidekick-2
Molecular Weight
Mass (kDA):
239.396 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q25.1 |
| Sequence: | 17; NC_000017.11 (73334384..73644481, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDK2
bosterbio.com/bosterbio-gene-info-cards/SDK2
References
PMID: 28397838 by Harripaul R., et al. Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.