SECISBP2 Antibodies

AND SECISBP2 ELISA kits, SECISBP2 Proteins

Many biological assays use antibodies to detect SECISBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SECISBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SECISBP2 antibodies...

We validate the specificity of these antibodies to SECISBP2 by testing them on tissues known to express SECISBP2 positively and negatively. Browse below to find the SECISBP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SECISBP2 Infographic by Boster Bio

All SECISBP2 Products

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Specificity

Applications

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Anti-SECISBP2 Antibody

Western blot analysis of extracts of various cell lines, using SECISBP2 antibody at 1:500 dilution

Immunofluorescence analysis of HeLa cells using SECISBP2 Rabbit pAb at dilution of 1:50

Immunohistochemistry of paraffin-embedded human liver damage using SECISBP2 antibody at dilution of 1:200

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06543
100ul

SECISBP2 (NM_024077) Human Over-expression Lysate

Human

$628
Cat # LS079048
20 µg, 100 µg

Anti-SECISBP2 Antibody Picoband®

Western blot analysis of SECISBP2 using anti-SECISBP2 antibody (A06543-4)

IF analysis of SECISBP2 using anti-SECISBP2 antibody (A06543-4) and anti-Beta Tubulin antibody (M01857-3)

Human

ELISA, IF, ICC, WB

$370
Cat # A06543-4
100 µg/vial

Anti-SECISBP2 Antibody

Human, Mouse, Rat

ELISA, IP, IF, ICC, WB

$370
Cat # A06543-3
100 μl/vial

SECISBP2 Overview

Facts about Selenocysteine insertion sequence-binding protein 2.

SECISBP2 3D structure. Source: alphafold

Selenocysteine insertion sequence-binding protein 2 (SECISBP2)

Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.

Gene Information

Human
Gene Name:	SECISBP2
Uniprot:	Q96T21
Entrez:	79048

Family

Belongs to:

No superfamily

Alternative Names

DKFZp686C09169; SBP2SECIS-binding protein 2; SECIS binding protein 2; selenocysteine insertion sequence binding protein 2; selenocysteine insertion sequence-binding protein 2

Molecular Weight

Mass (kDA):
95.462 kDA

Genomic Context


Human

Location:	9q22.2
Sequence:	9; NC_000009.12 (89318500..89367117)

Tissue Specificity

Expressed at high levels in testis.

Subcellular Localizations

[Isoform 1]: Nucleus.; [Isoform 2]: Mitochondrion.

Diseases

Growth Retardation
Myopathy
Thyroid Diseases
Congenital Myopathy (disorder)
Thyroid Hormone Resistance Syndrome
Dystrophy
Muscular Dystrophy
Pseudohypoparathyroidism
Hypoxia
Photosensitivity Disorders
Insulin Resistance
Telomere Shortening
Cardiovascular Diseases

Neoplasms
Cerebrovascular Accident
Azoospermia
Dwarfism
Multisystem Disorder
Mesothelioma
Neuroblastoma

Interacting Proteins

GOLGA2

Pathways

Translation
Selenocysteine Incorporation
Localization
Bone Maturation
Cell Death
Cytokine Secretion
Nuclear Export
Spermatogenesis

Lymphocyte Proliferation
Secretion

PTMs

Oxidation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SECISBP2

References

PMID: 12095701 by Lescure A., et al. cDNA cloning, expression pattern and RNA binding analysis of human selenocysteine insertion sequence (SECIS) binding protein 2.

PMID: 19004874 by Papp L.V., et al. Functional characterization of alternatively spliced human SECISBP2 transcript variants.