Semaphorin-5A Antibodies

AND SEMA5A ELISA kits, Semaphorin-5A Proteins

Many biological assays use antibodies to detect Semaphorin-5A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-5A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-5A antibodies...

We validate the specificity of these antibodies to Semaphorin-5A by testing them on tissues known to express SEMA5A positively and negatively. Browse below to find the SEMA5A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEMA5A Infographic by Boster Bio

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Semaphorin 5A (SEMA5A) (NM_003966) Human Over-expression Lysate

Human

$960
Cat # LS009037
20 µg, 100 µg

SEMA5A Overview

Facts about Semaphorin-5A.

SEMA5A 3D structure. Source: alphafold

Semaphorin-5A (SEMA5A)

Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3.

In glioma cells, SEMA5A stimulation of PLXNB3 leads to the disassembly of F-actin stress fibers, disruption of focal adhesions and mobile collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

Gene Information

Human
Gene Name:	SEMA5A
Uniprot:	Q13591
Entrez:	9037

Family

Belongs to:

semaphorin family

Alternative Names

FLJ12815; sema domain, seven thrombospondin repeats (type 1 and type 1-like); Sema F; SEMA5A; SEMAF; Semaphorin 5A; semaphorin F; semaphorin-5A; Semaphorin-F; semF; transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A