Serpin B3 Antibodies

AND SERPINB3 ELISA kits, Serpin B3 Proteins

Many biological assays use antibodies to detect Serpin B3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Serpin B3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Serpin B3 antibodies...

We validate the specificity of these antibodies to Serpin B3 by testing them on tissues known to express SERPINB3 positively and negatively. Browse below to find the SERPINB3 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERPINB3 Infographic by Boster Bio

All SERPINB3 Products

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Anti-SCCA1/2 SERPINB3 Antibody

13 Q&As

Western Blot analysis of Jurkat, 293 cells using SCCA1/2 Polyclonal Antibody

Western blot analysis of lysate from Jurkat cells, using SERPINB3/4 Antibody

Human

ELISA, IF, IHC, WB

$399
Cat # A04067
100μl

Anti-SERPINB3/4 Antibody

Western blot (WB) analysis of SERPINB3/4 polyclonal antibody at 1:500 dilution
Line1:THP-1 whole cell lysate
Line2:PC12 whole cell lysate
Line3:sp20 whole cell lysate

Human, Mouse, Rat

$405
Cat # A04067-1
100ul

Human Serpin B3/SSCA1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP29508
Starting from 20ug

Anti-SERPINB3 Mouse Monoclonal Antibody [Clone ID: OTI3C2]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB3 (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SERPINB3 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-SERPINB3 mouse monoclonal antibody

Dog, Human, Monkey, Rat

IHC, WB

$523
Cat # M04067
100 µl

Anti-SERPINB3 Mouse Monoclonal Antibody [Clone ID: OTI3G4]

Human

IF, IHC, WB

$523
Cat # M04067-1
100 µl

Anti-SerpinB3 Rabbit Monoclonal Antibody

Western blot analysis of SerpinB3 expression in A431 cell lysate

IHC analysis of SerpinB3 using anti-SerpinB3 antibody (M04067-2)

Human

IF, IHC, ICC, WB

$370
Cat # M04067-2
100 μl/vial

SERPINB3 (NM_006919) Human Over-expression Lysate

Human

$628
Cat # LS006317
20 µg, 100 µg

SERPINB3 Overview

Facts about Serpin B3.

SERPINB3 3D structure. Source: alphafold

Serpin B3 (SERPINB3)

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

Gene Information

Human
Gene Name:	SERPINB3
Uniprot:	P29508
Entrez:	6317

Family

Belongs to:

serpin family

Alternative Names

HsT1196; Protein T4-A; SCC; SCCA; SCCA1; SCCA1SCCA-1; SCCA-PD; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; Serpin B3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A

Molecular Weight

Mass (kDA):
44.565 kDA

Genomic Context


Human

Location:	18q21.33
Sequence:	18; NC_000018.10 (63655197..63661893, complement)

Tissue Specificity

Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

Subcellular Localizations

Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

Diseases

Carcinoma
Malignant Squamous Cell Neoplasm
Neoplasms
Malignant Neoplasms
Inflammation
Liver Diseases
Chronic Liver Disease
Liver Carcinoma
Liver Cirrhosis
Hepatitis
Asthma
Cell Invasion
Infective Disorder

Hyperplasia
Neoplasm Invasiveness
Mouth Neoplasms
Fibrosis
Epithelial Ovarian Cancer
Psoriasis
Autoimmune Diseases

Pathways

Cell Death
Programmed Cell Death
Blood Coagulation
Cell Proliferation
Coagulation
Pathogenesis
Cell Adhesion
Transport
Cell Migration
Immune Response
Proteolysis
Sensitization
Reverse Transcription

System Development
Cell Motility
Innate Immune Response
Cell Differentiation
Cell Communication
Cell Development
Localization

PTMs

Phosphorylation

Cleavage

Methylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB3

References

PMID: 1958219 by Suminami Y., et al. Squamous cell carcinoma antigen is a new member of the serine protease inhibitors.

PMID: 7724531 by Schneider S.S., et al. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.