SESTD1 Antibodies

AND SESTD1 ELISA kits, SESTD1 Proteins

Many biological assays use antibodies to detect SESTD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SESTD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SESTD1 antibodies...

We validate the specificity of these antibodies to SESTD1 by testing them on tissues known to express SESTD1 positively and negatively. Browse below to find the SESTD1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SESTD1 Infographic by Boster Bio

All SESTD1 Products

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Anti-SESTD1 Antibody

Western blot analysis of SESTD1 in rat brain tissue lysate with SESTD1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of SESTD1 in human brain tissue with SESTD1 antibody at 5 μg/mL

Immunofluorescence of SESTD1 in Human Brain cells with SESTD1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A10698
0.1 mg

Anti-Solo (SESTD1) Mouse Monoclonal Antibody [Clone ID: OTI2E7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SESTD1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-SESTD1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-SESTD1 mouse monoclonal antibody

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M10698
100 µl

Anti-Solo/SESTD1 Antibody Picoband®

Western blot analysis of Solo/SESTD1 using anti-Solo/SESTD1 antibody (A10698-1)

Flow Cytometry analysis of Daudi cells using anti-Solo/SESTD1 antibody (A10698-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A10698-1
100 μg/vial

Solo (SESTD1) (NM_178123) Human Over-expression Lysate

Human

$628
Cat # LS091404
20 µg, 100 µg

SESTD1 Overview

Facts about SEC14 domain and spectrin repeat-containing protein 1.

SESTD1 3D structure. Source: alphafold

SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids such as phosphatidylcholine, phosphatidylserine, and phosphatidylinositol.

The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

Gene Information

Human
Gene Name:	SESTD1
Uniprot:	Q86VW0
Entrez:	91404

Family

Belongs to:

SOLO family

Alternative Names

DKFZp434O0515; Huntingtin-interacting protein-like protein; Protein Solo; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; SOLO

Molecular Weight

Mass (kDA):
79.348 kDA

Genomic Context


Human

Location:	2q31.2
Sequence:	2; NC_000002.12 (179101678..179264832, complement)

Tissue Specificity

Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature.

Interacting Proteins

GPS2
STMN1

Pathways

Smooth Muscle Contraction
Cell Proliferation
Regulation Of Cell Proliferation
Muscle Contraction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SESTD1

References

PMID: 20164195 by Miehe S., et al. The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.