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- Table of Contents
Designing an IHC experiment for Setd3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SETD3 IHC GuideFacts about Actin-histidine N-methyltransferase.
Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1 (PubMed:21832073). .
| Mouse | |
|---|---|
| Gene Name: | Setd3 |
| Uniprot: | Q91WC0 |
| Entrez: | 52690 |

| Belongs to: |
|---|
| class V-like SAM-binding methyltransferase superfamily |

C14orf154; chromosome 14 open reading frame 154; DKFZp761E1415; EC 2.1.1.43; FLJ23027; MGC87236; SET domain containing 3; SET domain-containing protein 3
Mass (kDA):
67.176 kDA

| Mouse | |
|---|---|
| Location: | 12 F1|12 59.23 cM |
| Sequence: | 12; |
Prominently expressed in the heart and skeletal muscles and is also detected weakly in the stomach, small intestine, and colon.



PMID: 16008511 by Ishii H., et al. Differentially expressed genes in endothelial differentiation.
PMID: 21832073 by Eom G.H., et al. Histone methyltransferase SETD3 regulates muscle differentiation.