SF3A1 Antibodies

AND SF3A1 ELISA kits, SF3A1 Proteins

Many biological assays use antibodies to detect SF3A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SF3A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SF3A1 antibodies...

We validate the specificity of these antibodies to SF3A1 by testing them on tissues known to express SF3A1 positively and negatively. Browse below to find the SF3A1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SF3A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SF3A1 IHC Guide

SF3A1 Infographic by Boster Bio

All SF3A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SF3A1 Antibody Picoband®

Western blot analysis of SF3A1 using anti-SF3A1 antibody (A05483-1)

IHC analysis of SF3A1 using anti-SF3A1 antibody (A05483-1)

+10

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A05483-1
100 μg/vial

Anti-Zebrafish SF3A1 Antibody

IHC analysis of SF3A1 using anti-SF3A1 antibody (AZQ90X41)

Zebrafish

IF, IHC

$470
Cat # AZQ90X41
100 μg/vial

SF3A1 (NM_005877) Human Over-expression Lysate

Human

$628
Cat # LS010291
20 µg, 100 µg

SF3A1 Overview

Facts about Splicing factor 3A subunit 1.

SF3A1 3D structure. Source: alphafold

Splicing factor 3A subunit 1 (SF3A1)

Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.

May also be involved in the assembly of the 'E' complex. .

Gene Information

Human
Gene Name:	SF3A1
Uniprot:	Q15459
Entrez:	10291

Family

Belongs to:

No superfamily

Alternative Names

pre-mRNA processing 21; pre-mRNA splicing factor SF3a (120 kDa subunit); Prp21; PRPF21; SAP 114; SAP114splicing factor 3a, subunit 1, 120kD; SF3a120; spliceosome associated protein 114; Spliceosome-associated protein 114; splicing factor 3 subunit 1; splicing factor 3A subunit 1; splicing factor 3a, subunit 1, 120kDa

Molecular Weight

Mass (kDA):
88.886 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (30331988..30356894, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Acute-phase Reaction
Neurofibromatosis 2
Malignant Neoplasms
Neoplasms
Nervousness
Malignant Neoplasm Of Breast

Mammary Neoplasms

Interacting Proteins

MAP1LC3C
PRPF40A
RBM10
SF1
SF3A2

SF3A3
SP1

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SF3A1

References

PMID: 7489498 by Kraemer A., et al. Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae.

PMID: 10882114 by Das R., et al. Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.