Epsilon-sarcoglycan Antibodies

AND SGCE ELISA kits, Epsilon-sarcoglycan Proteins

Many biological assays use antibodies to detect Epsilon-sarcoglycan, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Epsilon-sarcoglycan in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Epsilon-sarcoglycan antibodies...

We validate the specificity of these antibodies to Epsilon-sarcoglycan by testing them on tissues known to express SGCE positively and negatively. Browse below to find the SGCE antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SGCE Infographic by Boster Bio

All SGCE Products

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Figures

Specificity

Applications

Price

Anti-Epsilon-sarcoglycan SGCE Antibody

Western blot analysis of extracts of various cell lines, using SGCE antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A02507
100ul

SGCE (NM_001099400) Human Over-expression Lysate

Human

$960
Cat # LS008910
20 µg, 100 µg

Anti-SGCE Antibody Picoband®

Western blot analysis of SGCE using anti-SGCE antibody (A02507-1)

IHC analysis of SGCE using anti-SGCE antibody (A02507-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02507-1
100 μg/vial

Anti-Zebrafish SGCE Antibody Picoband®

Western blot analysis of SGCE using anti-SGCE antibody (AZQ6DHH1)

Zebrafish

$470
Cat # AZQ6DHH1
100 μg/vial

SGCE Overview

Facts about Epsilon-sarcoglycan.

SGCE 3D structure. Source: alphafold

Epsilon-sarcoglycan (SGCE)

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. .

Gene Information

Human
Gene Name:	SGCE
Uniprot:	O43556
Entrez:	8910

Family

Belongs to:

sarcoglycan alpha/epsilon family

Alternative Names

dystonia 11, myoclonic; DYT11; epsilon-Sarcoglycan; Epsilon-SG; ESG; Sarcoglycan epsilon; sarcoglycan, epsilon; SGCE

Molecular Weight

Mass (kDA):
49.851 kDA

Genomic Context


Human

Location:	7q21.3
Sequence:	7; NC_000007.14 (94584980..94656205, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cell membrane, sarcolemma; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cell projection, dendrite. Golgi apparatus.

Diseases

Dystonia Disorders
Myoclonus
Movement Disorders
Myoclonic Dystonia
Dysmyelopoietic Syndromes
Obsessive-compulsive Disorder
Benign Mixed Epithelial And Stromal Tumor Of Kidney
Organic Writer's Cramp
Muscle Cramp
Osteochondritis Dissecans
Depressive Disorder
Dystonia, Primary

Malignant Neoplasms
Chorea
Benign Hereditary Chorea
Tissue Adhesions
Carcinoma
Hereditary Diseases

Pathways

Methylation
Pathogenesis
Dna Methylation
Cell Adhesion
Reflex
Transport
Dna Hypermethylation
Dna Hypomethylation
Brain Development
Fertilization
Dna Demethylation
Proteolysis
Neurogenesis

Spermatogenesis
Cell Cycle Arrest
Embryo Development
Embryo Implantation
Cell Cycle
Histone Acetylation
Cognition

PTMs

Methylation
Demethylation

Phosphorylation
Acetylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SGCE

References

PMID: 9475163 by McNally E.M., et al. Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.

PMID: 15193417 by Nishiyama A., et al. Identification and characterization of epsilon-sarcoglycans in the central nervous system.