SGK2 Antibodies

AND SGK2 ELISA kits, SGK2 Proteins

Many biological assays use antibodies to detect SGK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SGK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SGK2 antibodies...

We validate the specificity of these antibodies to SGK2 by testing them on tissues known to express SGK2 positively and negatively. Browse below to find the SGK2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SGK2 Infographic by Boster Bio

All SGK2 Products

Product

Figures

Specificity

Applications

Price

Anti-SGK2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04918
100ul

SGK2 (NM_170693) Human Recombinant Protein

$1249
Cat # PROTQ9HBY8
20 µg

SGK2 (NM_170693) Human Over-expression Lysate

Human

$628
Cat # LS010110
100 µg

SGK2 Overview

Facts about Serine/threonine-protein kinase Sgk2.

SGK2 3D structure. Source: alphafold

Serine/threonine-protein kinase Sgk2 (SGK2)

Serine/threonine-protein kinase which is involved in the regulation of a wide array of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.

3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. .

Gene Information

Human
Gene Name:	SGK2
Uniprot:	Q9HBY8
Entrez:	10110

Family

Belongs to:

protein kinase superfamily

Alternative Names

dJ138B7.2; EC 2.7.11; EC 2.7.11.1; H-SGK2; serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; Serum/glucocorticoid-regulated kinase 2; SGK2; Sgkl

Molecular Weight

Mass (kDA):
47.604 kDA

Genomic Context


Human

Location:	20q13.12
Sequence:	20; NC_000020.11 (43559027..43585633)

Tissue Specificity

Highly expressed in liver, kidney and pancreas, and at lower levels in brain.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Neoplasms
Ischemia
Kidney Diseases
Diabetic Nephropathy
Hypertensive Disease
Sclerosis
Primary Lateral Sclerosis
Deafness Congenital
Uterine Cervical Neoplasm
Dehydration
Amyotrophic Lateral Sclerosis
Sequelae Aspects

Hypernatremia
Carcinoma
Injury To Kidney
Cardiovascular Diseases
Patient Dependence On
Deprivation Of Water
Bartter Disease

Pathways

Transport
Cell Proliferation
Excretion
Regulation Of Transport
Amino Acid Transport
Localization
Citrate Transport
Cell Death

Renal Sodium Excretion
Intestinal Absorption
Secretion

PTMs

Phosphorylation
Carboxylation

Reduction
Ubiquitination

Research Areas

GPCR
Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SGK2

References

PMID: 10548550 by Kobayashi T., et al. Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

PMID: 12590200 by Henke G., et al. Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.