SGSH Antibodies

AND SGSH ELISA kits, SGSH Proteins

Many biological assays use antibodies to detect SGSH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SGSH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SGSH antibodies...

We validate the specificity of these antibodies to SGSH by testing them on tissues known to express SGSH positively and negatively. Browse below to find the SGSH antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SGSH? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SGSH IHC Guide

SGSH Infographic by Boster Bio

All SGSH Products

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Product

Figures

Specificity

Applications

Price

Anti-HSS/SGSH Antibody Picoband®

IHC analysis of HSS/SGSH using anti-HSS/SGSH antibody (A04608-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A04608-1
100 μg/vial

Anti-SGSH Rabbit Monoclonal Antibody

Western Blot analysis of HEK-293 whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-SGSH rabbit mAb

Human

IF, IHC, ICC, WB

$146
Cat # M04608-1
20μL, 40μL, 100μL, 200μL

SGSH (NM_000199) Human Over-expression Lysate

Human

$628
Cat # LS006448
20 µg, 100 µg

SGSH (NM_000199) Human Recombinant Protein

Coomassie blue staining of purified SGSH protein

$1249
Cat # PROTP51688
20 µg

SGSH Overview

Facts about N-sulphoglucosamine sulphohydrolase.

SGSH 3D structure. Source: alphafold

N-sulphoglucosamine sulphohydrolase (SGSH)

Catalyzes a step in lysosomal heparan sulfate degradation. .

Gene Information

Human
Gene Name:	SGSH
Uniprot:	P51688
Entrez:	6448

Family

Belongs to:

sulfatase family

Alternative Names

heparan sulfate sulfatase; HSS; HSSN-sulphoglucosamine sulphohydrolase; MPS3A; MPS3Asulphamidase; N-sulfoglucosamine sulfohydrolase; SFMD; SFMDEC 3.10.1.1; SGSH; Sulfamidase; Sulfoglucosamine sulfamidase; Sulphamidase

Molecular Weight

Mass (kDA):
56.695 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (80200668..80220333, complement)

Subcellular Localizations

Lysosome.

Diseases

Mucopolysaccharidoses
Mucopolysaccharidosis Iii
Mps Iii A
Lysosomal Storage Diseases
Nervousness
Nerve Degeneration
Neuropathology Disease
Mucopolysaccharidosis Type Iiib
Neurodegenerative Disorders
Mucopolysaccharidosis I
Storage Disease
Mucopolysaccharidosis Type Iiic

Pfaundler-hurler Syndrome
Dementia
Sleep Disorders
Dog Diseases
Tissue Damage
Neuronal Ceroid-lipofuscinoses

Pathways

Excretion
Transport
Sulfation
Translation
Immune Response
Pathogenesis
Humoral Immune Response

Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SGSH

References

PMID: 7493035 by Scott H.S., et al. Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome.

PMID: 24816101 by Sidhu N.S., et al. Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.