SH2D3C Antibodies

AND SH2D3C ELISA kits, SH2D3C Proteins

Many biological assays use antibodies to detect SH2D3C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH2D3C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH2D3C antibodies...

We validate the specificity of these antibodies to SH2D3C by testing them on tissues known to express SH2D3C positively and negatively. Browse below to find the SH2D3C antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH2D3C Infographic by Boster Bio

All SH2D3C Products

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Specificity

Applications

Price

Anti-SH2D3 SH2D3C Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04497
100ul

NSP3 (SH2D3C) (NM_005489) Human Recombinant Protein

Coomassie blue staining of purified SH2D3C protein

$1249
Cat # PROTQ8N5H7
20 µg

NSP3 (SH2D3C) (NM_170600) Human Over-expression Lysate

NSP3 (SH2D3C) Human Over-expression Lysates NM_005489

Human

$628
Cat # LS010044
20 µg, 100 µg

Anti-SH2D3C Antibody Picoband®

Western blot analysis of SH2D3C using anti-SH2D3C antibody (A04497-1)

Flow Cytometry analysis of HEL cells using anti-SH2D3C antibody (A04497-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04497-1
100 µg/vial

SH2D3C Overview

Facts about SH2 domain-containing protein 3C.

SH2D3C 3D structure. Source: alphafold

SH2 domain-containing protein 3C (SH2D3C)

Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity).

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Gene Information

Human
Gene Name:	SH2D3C
Uniprot:	Q8N5H7
Entrez:	10044

Family

Belongs to:

No superfamily

Alternative Names

CHAT; Novel SH2-containing protein 3; NSP3FLJ39664; PRO34088; SH2 domain containing 3C; SH2 domain-containing 3C; SH2 domain-containing protein 3C

Molecular Weight

Mass (kDA):
94.411 kDA

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (127738317..127778666, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Cytoplasm. Membrane; Peripheral membrane protein. Associated with the membrane when EGF-stimulated. Found at ruffling membranes (By similarity).

Diseases

Tissue Adhesions
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Cell Invasion
Stomach Neoplasms
Kallmann Syndrome
Anosmia
Malignant Neoplasm Of Stomach
Hypoplasia

Lymphopenia
Neoplasms
Nervousness
Mammary Neoplasms, Experimental
Bulla

Interacting Proteins

BCAR1
KIT
MET

Pathways

Cell Migration
Cell Adhesion
Cell Activation
T Cell Activation
Localization
Actin Cytoskeleton Organization
Regulation Of Cell Cycle
Regulation Of Cell Adhesion
Cell Development
Immune Response
Neurogenesis
Cell Fate Determination
Humoral Immune Response

Cell Maturation
Cytoskeleton Organization
Cytokine Production
Translation
Axon Guidance
Cell Cycle
Cell Growth

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH2D3C

References

PMID: 10187783 by Lu Y., et al. NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress- activated protein kinase signaling pathway.

PMID: 22081014 by Mace P.D., et al. NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.